ID A0A3G2JPJ9_9ACTN Unreviewed; 655 AA.
AC A0A3G2JPJ9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Acetoacetate--CoA ligase {ECO:0000313|EMBL:AYN42412.1};
DE EC=6.2.1.16 {ECO:0000313|EMBL:AYN42412.1};
GN ORFNames=D9753_29905 {ECO:0000313|EMBL:AYN42412.1};
OS Streptomyces dangxiongensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1442032 {ECO:0000313|EMBL:AYN42412.1, ECO:0000313|Proteomes:UP000268329};
RN [1] {ECO:0000313|EMBL:AYN42412.1, ECO:0000313|Proteomes:UP000268329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z022 {ECO:0000313|EMBL:AYN42412.1,
RC ECO:0000313|Proteomes:UP000268329};
RA Zhang B.;
RT "The genome of Streptomyces dangxiongensis Z022.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP033073; AYN42412.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3G2JPJ9; -.
DR KEGG; sdd:D9753_29905; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000268329; Chromosome.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd05943; AACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:AYN42412.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000268329}.
FT DOMAIN 41..97
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 99..472
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 539..614
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 655 AA; 72254 MW; 80A38E81071067D2 CRC64;
MSTANPKPLW QPDPQRIAQA RITQFQAWAA AHHGAPADGG YPALHRWSVD QLDTFWQAVT
EWFDVRFSTP YARVLGDRAM PGAHWFPGAT LNYAEHALRA AAGRADEPAL LYVDETHEPR
PVTWSELRRE VGSLAAALRT LGVRPGDRVS GYLPNIPQAV VALLATAAVG AVWTSCAPDF
GARSVLDRFQ QVEPVVLFTV DGYRYGGKEH DRRETVAELR RELPTLRAVV HIPLLGTEAP
EGALEWSALT TGDIEPVFEQ VPFDHPLWVL YSSGTTGLPK AIVQSQGGIL VEHLKQLGLH
CDLGPEDRFF WYTSTGWMMW NFLVSGLLTG TTIVLYDGSP GYPDTGAQWR IAERTGATLY
GTSAAYVMAC RKAGVHPARD HDLSTVKCVA TTGSPLPPDG FRWLHDEVRD DLWIASVSGG
TDVCSCFAGA VPTLPVYTGE LQAPGLGTDL QSWDPSGKPL VDEVGELIVT NPMPSMPIRF
WNDPDGSRYH DSYFDTYPGV WRHGDWITVT SRGTVIIHGR SDSTLNRQGV RMGSADIYEV
VERLPEIHES LVIGIEQPDG GYWMPLFVHL APDATLDESL LDRIKRSIRE QLSPRHIPDE
IIEVPGIPHT LTGKRIEVPV KRLLQGTPLE KAVNPGSIDN LTLLGFYEEL ARERA
//
