ID   A0A3G3GM46_9BACT        Unreviewed;      1028 AA.
AC   A0A3G3GM46;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Signal transduction histidine kinase internal region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DTQ70_08965 {ECO:0000313|EMBL:AYQ32301.1};
OS   Runella sp. SP2.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae; Runella.
OX   NCBI_TaxID=2268026 {ECO:0000313|EMBL:AYQ32301.1, ECO:0000313|Proteomes:UP000270973};
RN   [1] {ECO:0000313|EMBL:AYQ32301.1, ECO:0000313|Proteomes:UP000270973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SP2 {ECO:0000313|EMBL:AYQ32301.1,
RC   ECO:0000313|Proteomes:UP000270973};
RA   Jin H.M.;
RT   "Genome sequence of Runella sp. SP1.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP031030; AYQ32301.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3G3GM46; -.
DR   KEGG; rup:DTQ70_08965; -.
DR   OrthoDB; 9809670at2; -.
DR   Proteomes; UP000270973; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR011110; Reg_prop.
DR   InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR011123; Y_Y_Y.
DR   PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR   PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR   Pfam; PF06580; His_kinase; 1.
DR   Pfam; PF07494; Reg_prop; 1.
DR   Pfam; PF07495; Y_Y_Y; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000270973};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        770..789
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          699..761
FT                   /note="Two component regulator three Y"
FT                   /evidence="ECO:0000259|Pfam:PF07495"
FT   DOMAIN          812..889
FT                   /note="Signal transduction histidine kinase internal
FT                   region"
FT                   /evidence="ECO:0000259|Pfam:PF06580"
FT   COILED          794..821
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1028 AA;  116111 MW;  FEC42C20B76BA20B CRC64;
     MGIVQNIDWK NMRLKGGLLL YLLGWGIPSL FAQVFQNAWV ENFDNRNGLS QNTVWSISQD
     SRGFLWVGTD DGLLRYDGYQ FKPYRAQIGK AAGGLPSNSI RQLFHNGDEH LWVGTRNGIA
     QLNILTDSIR TYLPNVRIRK ILPGAKGKLW VGTNKGLYFL DTKSKRTYCK IPKLNILNAA
     QLDTDRLLIS TSDNYWLLDV KKNKYKVVSF GLAPDNDIRP MQVYNNLIWI GVENEGVWVF
     DSHSLKLVKK YSLRAFFPEL ITFPIRSMTI GKNGRCWLSL QSGLVCLDTK TEKMDFLPSD
     LTYQRLNSLK GSPLNDIFED NSGLVWVGSN NSGLNKINLR LGKFRTINQD NGLNYNFVLS
     FAESGENLLV GTDGEGINVW NKKTGKVRVS KPETEGRSQV FAMIEVEPSL FWGATSNGLV
     QFDAKKGNFT APSLACKAAF DTLQSTAIRT IYMDSRKRVW MGTAKGLFTF DYPTKAYRFW
     GNASGYDDLI NSFKEDSKGT VWIGRGVGLQ KYSPINETIE PVPLVIPSTN TEVGDVSSVN
     LSSDSVLWIS SYRVGFGKYN PLSKQFKLYT TDDGLPNSIV YGSLVDDNGQ VWMSTNMGLA
     RFNPKNETFT AFDVHDGIQN NEFNGGAYIK LASGEMAFGG VNGFTIFQPT GLQRRGSPSP
     VAITEVKVMN HSVNVFGKGI IETSYTENFL SFEFAALDFI SPQKNQYAYQ LVGVDKNWVS
     SGNRHFVSYS QIPPGEYTFK VKASNSDGVW NEKPTILKVR VTAPFWTKDW FRLLVIMAGV
     GALVVFFTGR IRRIQEREKE KAMLNRQIAA LEMKALRAQM NPHFIFNCLN SINNFILHDQ
     NHQASKYLTK FSKLIRQILD NTDTPLQPIE RIMTFMNLYV ELEQMRFGKN KFDFEIKVDP
     RLEAHETVFP TMMIQPHVEN AIWHGLMHRT EQGKIILSFQ RETTTLVSCT IEDNGVGRAK
     SKEISKQLSP SRKSKGTQNV LESIETFNRQ YNTEGAKIII DDLYDQTGEP LGTKVKIVLP
     DIAQFKLC
//