ID A0A3G3GYZ8_9BACT Unreviewed; 629 AA.
AC A0A3G3GYZ8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN Name=acs {ECO:0000313|EMBL:AYQ36512.1};
GN ORFNames=DTQ70_27945 {ECO:0000313|EMBL:AYQ36512.1};
OS Runella sp. SP2.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae; Runella.
OX NCBI_TaxID=2268026 {ECO:0000313|EMBL:AYQ36512.1, ECO:0000313|Proteomes:UP000270973};
RN [1] {ECO:0000313|EMBL:AYQ36512.1, ECO:0000313|Proteomes:UP000270973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP2 {ECO:0000313|EMBL:AYQ36512.1,
RC ECO:0000313|Proteomes:UP000270973};
RA Jin H.M.;
RT "Genome sequence of Runella sp. SP1.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP031030; AYQ36512.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3G3GYZ8; -.
DR KEGG; rup:DTQ70_27945; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000270973; Chromosome.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:AYQ36512.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000270973}.
FT DOMAIN 9..64
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 66..452
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 514..592
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 629 AA; 70205 MW; C6ABA0DDD1A41768 CRC64;
MLIRTFEEYQ AAYQHSVEDP EGFWAEVAQE FKWHKPWKKV LDWNFTGPDV KWFVNGKTNI
TENALDRHLR ELGNHPAIIW EPNDPHEPSV TLTYKMLHDQ VCRFSNVLKR NGVQKGDRVC
IYLPMVPEAA IAMLACARIG AIHSVVFGGF SAQSLTDRIN DSDCKVIITS DGAARGPKNI
PMKDTVDDAL IGCRSVEKVI VLTHTRTPIS MIKGRDVWWE SEMKQVTSDC PPEVMDSEDP
LFILYTSGST GKPKGVVHST GGYMVYSAYT FQNVFQYEPG QIHFCTADVG WITGHSYIVY
GPLLSGATTL MFEGVPTYPD AGRFWDIVDK HKVDILYTAP TAIRSLMGFG LKYVEGKDLS
SLKVLGSVGE PINEEAWNWY NENIGKGRCP IVDTWWQTET GGILISPIAG VTKTKPTYAT
LPLPGVQPIL VDENGVEIEG NGVSGNLCIK YPWPSIIRTT WGDHERCRQT YFSTYPERYF
TGDGCLRDED GYYRITGRVD DVLNVSGHRI GTAEVENAIN MHADVIESAV VGYPHDIKGQ
GIYAFVICEN VLDDEDLSRR DILATVTRII GPIAKPDKIQ FVRGLPKTRS GKIMRRILRK
IAEGDTSNLG DTTTLLDPTV VEDIKEGAL
//
