ID   A0A3G3JZ06_9BACL        Unreviewed;       333 AA.
AC   A0A3G3JZ06;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:AYQ73480.1};
GN   ORFNames=EAV92_13375 {ECO:0000313|EMBL:AYQ73480.1};
OS   Cohnella candidum.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Cohnella.
OX   NCBI_TaxID=2674991 {ECO:0000313|EMBL:AYQ73480.1, ECO:0000313|Proteomes:UP000269097};
RN   [1] {ECO:0000313|EMBL:AYQ73480.1, ECO:0000313|Proteomes:UP000269097}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=18JY8-7 {ECO:0000313|EMBL:AYQ73480.1,
RC   ECO:0000313|Proteomes:UP000269097};
RA   Srinivasan S., Kim M.K.;
RT   "Genome Sequence of Cohnella sp.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072, ECO:0000256|RuleBase:RU361277}.
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DR   EMBL; CP033433; AYQ73480.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3G3JZ06; -.
DR   KEGG; coh:EAV92_13375; -.
DR   Proteomes; UP000269097; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR   CDD; cd08234; threonine_DH_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43401; L-THREONINE 3-DEHYDROGENASE; 1.
DR   PANTHER; PTHR43401:SF2; L-THREONINE 3-DEHYDROGENASE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000269097};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          4..321
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   333 AA;  36647 MW;  6CC21CDAC9CA5785 CRC64;
     MKALVMEKPH QAVVKEVPYP APRQGEVVIE VVQVGICGTD FHIFEGEFLS PYPLIPGHEF
     SGVVHELGEG VEGFRIGDRV TADPSLFCGR CRYCLTNRGN QCENWGALGN TVDGSMAEYV
     AVPARNVVKI PDGMTFETAA FIEPMACVVH AMNRLQLQAG QSVLLYGAGA MGLQLVQSLS
     RLGASRLTVA DVSDRKLELA RELGATDAVN VLRERQRLDG EKFDVVVDAT GIPSVIEEAM
     THLGKTAKYL QFGVTPKHAE IRVNPFDLYH KDWTILGSMA INYTFLNAFE WVKAGRVQLE
     PLVSKVITLE ETPAFLAKPK DPELLKVQIK IRD
//