ID   A0A3G6ZIY6_9MICO        Unreviewed;       347 AA.
AC   A0A3G6ZIY6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Alpha-ketoacid dehydrogenase subunit beta {ECO:0000313|EMBL:AZC12691.1};
GN   ORFNames=DT073_02280 {ECO:0000313|EMBL:AZC12691.1};
OS   Microbacterium sp. ABRD28.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Microbacterium.
OX   NCBI_TaxID=2268461 {ECO:0000313|EMBL:AZC12691.1, ECO:0000313|Proteomes:UP000280903};
RN   [1] {ECO:0000313|EMBL:AZC12691.1, ECO:0000313|Proteomes:UP000280903}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ABRD_28 {ECO:0000313|EMBL:AZC12691.1};
RA   Jin H.M.;
RT   "Genome sequence of Microbacterium sp. ABRD28.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR   EMBL; CP031015; AZC12691.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3G6ZIY6; -.
DR   OrthoDB; 3457658at2; -.
DR   Proteomes; UP000280903; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR   CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR033248; Transketolase_C.
DR   PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000280903}.
FT   DOMAIN          27..202
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   347 AA;  37210 MW;  67D8D213346E6EF2 CRC64;
     MTTAQPISTP APEPAGDPAD AGVIRSLPLS KALNLGLRAA LAGSDRVLLM GEDIGRLGGV
     FRVTEGLQAE FGDRRVIDTP LAESGIVGTA IGLAMAGFRP VLEIQFDGFV FPAFDQITSQ
     LAKITNRHEG AVRMPIVIRI PYGGHIGAVE HHQESPEAYF THTPGLRVVS PSTPNDAYWM
     MQEAIASDDP VIFLEPKSRY WQKGEVDTRA PALPLHASRL VRRGTDVTLV GHGAMVHTLL
     QAAALAESEG TSCEVIDLRS LSPVDYGPVL DSVRRTGRMV YAQEAPGFTS LGSEVAATVM
     EKAFFALESP VLRVSGFDTP FPPAKLEGTY LPDADRILEA VDRALAY
//