ID A0A3G8JSI4_9ACTN Unreviewed; 505 AA.
AC A0A3G8JSI4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Cardiolipin synthase {ECO:0000313|EMBL:AZG48071.1};
DE EC=2.7.8.- {ECO:0000313|EMBL:AZG48071.1};
GN Name=cls {ECO:0000313|EMBL:AZG48071.1};
GN ORFNames=D7316_04684 {ECO:0000313|EMBL:AZG48071.1};
OS Gordonia insulae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=2420509 {ECO:0000313|EMBL:AZG48071.1, ECO:0000313|Proteomes:UP000271469};
RN [1] {ECO:0000313|EMBL:AZG48071.1, ECO:0000313|Proteomes:UP000271469}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMS17-SY073 {ECO:0000313|EMBL:AZG48071.1,
RC ECO:0000313|Proteomes:UP000271469};
RA Kim Y.S., Kim S.B.;
RT "Gordonia insulae sp. nov., isolated from an island soil.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC sn-glycero-3-phosphate + choline + H(+); Xref=Rhea:RHEA:14445,
CC ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58608; EC=3.1.4.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000798};
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DR EMBL; CP033972; AZG48071.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3G8JSI4; -.
DR KEGG; gom:D7316_04684; -.
DR Proteomes; UP000271469; Chromosome.
DR GO; GO:0004630; F:phospholipase D activity; IEA:RHEA.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006793; P:phosphorus metabolic process; IEA:UniProt.
DR CDD; cd09140; PLDc_vPLD1_2_like_bac_1; 1.
DR CDD; cd09143; PLDc_vPLD1_2_like_bac_2; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR InterPro; IPR015679; PLipase_D_fam.
DR PANTHER; PTHR18896:SF76; PHOSPHOLIPASE; 1.
DR PANTHER; PTHR18896; PHOSPHOLIPASE D; 1.
DR Pfam; PF00614; PLDc; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000271469};
KW Transferase {ECO:0000313|EMBL:AZG48071.1}.
FT DOMAIN 138..165
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 353..380
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT REGION 168..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 505 AA; 56428 MW; 46E9400025A0832E CRC64;
MTSIDDARGG ASGALLVPGQ NCYGIGRADR FACIIDAADY FRFAKQAMLG ARKRIMLIGW
DFDTRIEFEP EEQTLDGPND LGDFLNWLPD HQPGLEIHLL KWSVGAFTAI TRGMTPVFLA
NLATNRNVHL EIDTRHPLRG AHHQKIVVID DRIAFCGGID MTVDRWDRSD HRDDHPRRVE
PNGNSYGPWH DATAAVDGDA ARLVGDIARQ RWLVATGEDL APVDDVDTDP WPDQLAPTMR
SVDVAVARTL PELDQQDEVR EIEQLYLDAI RSAKRFLYIE SQYLAARVIA DAIAQRLRES
DGPEIVVVLP RHADGWLEQK AMDGARRRLL HQLWDADEHQ HFRAYHPVTA TGGPIYVHAK
VLVMDDRLLR VGSSNLNNRS LGLDSECDLA VEVSADDPSA AEHRRSIVGV RDRLIAEHLA
VPVAEFRDEL ERRQSLIGAI DHLRGEGKTL ERFDAGTIAD EESPLAENDL MDPESAKGNP
VLTRVIRFVA GRPLRRLSST GTERP
//
