ID A0A3G8YIS6_9DEIO Unreviewed; 610 AA.
AC A0A3G8YIS6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Efflux RND transporter periplasmic adaptor subunit {ECO:0000313|EMBL:AZI44660.1};
GN ORFNames=EHF33_17330 {ECO:0000313|EMBL:AZI44660.1};
OS Deinococcus psychrotolerans.
OG Plasmid unnamed1 {ECO:0000313|EMBL:AZI44660.1,
OG ECO:0000313|Proteomes:UP000276417}.
OC Bacteria; Deinococcota; Deinococci; Deinococcales; Deinococcaceae;
OC Deinococcus.
OX NCBI_TaxID=2489213 {ECO:0000313|EMBL:AZI44660.1, ECO:0000313|Proteomes:UP000276417};
RN [1] {ECO:0000313|EMBL:AZI44660.1, ECO:0000313|Proteomes:UP000276417}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S14-83T {ECO:0000313|EMBL:AZI44660.1,
RC ECO:0000313|Proteomes:UP000276417};
RC PLASMID=unnamed1 {ECO:0000313|EMBL:AZI44660.1,
RC ECO:0000313|Proteomes:UP000276417};
RA Tian J.;
RT "Deinococcus shelandsis sp. nov., isolated from South Shetland Islands soil
RT of Antarctica.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP034185; AZI44660.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3G8YIS6; -.
DR KEGG; dph:EHF33_17330; -.
DR OrthoDB; 9784685at2; -.
DR Proteomes; UP000276417; Plasmid unnamed1.
DR GO; GO:0019898; C:extrinsic component of membrane; IEA:InterPro.
DR GO; GO:1990195; C:macrolide transmembrane transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 2.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 2.
DR Gene3D; 6.10.140.1990; -; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR030190; MacA_alpha-hairpin_sf.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; Plasmid {ECO:0000313|EMBL:AZI44660.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 48..248
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 130..208
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 297..343
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 610 AA; 61710 MW; 191A0C4074B00216 CRC64;
MTAAQTPEGN TPDLKKPDLQ APAPQAKKTP PARRALGLTV GLLVALGAGG IVWWYAYNGS
QHVSTDNARV AANTANIVPE IPGRVLQWNV AVGTTVTAGQ VIGQIDTSTV AQSSAANAGA
LSQTAPLTAS RSLIRAPISG QVIQSSALVG QLVATGQSLA VIADDSSAYI SANVKEDQIS
KVKLGQPVHV TLDALPGQTL SGRVQQIGQA TASTFSLLPS GGADNGNFTK VAQVIPVSIY
LSTADRSKLL PGSSASVTID LTDPPSTPTS VKTATAAPEP LKVQLNVVGT LTSGNDVTIA
AQVAGNVTKV GAQVGDNVTK GEVLARIDDS NLQAQLAGAQ AALSQVQNGG NSAQANLQLA
ASTLDRVSAV YKLGGVSRQD LQNAQTQYTN AQVAAQNAGG GAVEAAQANV QNLKLMIGKA
VVVSPIDGVV SARNVEVGEV AAPGVPLMTI VQNDPRKIVA TIPAAQANLI KAGQPMQIKF
DAFPNRSYSA KITSINPASV ATGDFYPIEA RLDAANAELR AGMVATGTIN ADVSAGSPTV
PSSAIARIGA QNYVYVVKDG KAVRTPIQTG LSGTAGGQAE VAVNGGLPSG AQIVTSNVNA
LWDGAPVKGN
//
