ID   A0A3G8ZKS4_9ACTN        Unreviewed;       537 AA.
AC   A0A3G8ZKS4;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=DNA polymerase Y family protein {ECO:0000313|EMBL:AZI57810.1};
GN   ORFNames=EH165_06260 {ECO:0000313|EMBL:AZI57810.1};
OS   Nakamurella antarctica.
OC   Bacteria; Actinomycetota; Actinomycetes; Nakamurellales; Nakamurellaceae;
OC   Nakamurella.
OX   NCBI_TaxID=1902245 {ECO:0000313|EMBL:AZI57810.1, ECO:0000313|Proteomes:UP000268084};
RN   [1] {ECO:0000313|EMBL:AZI57810.1, ECO:0000313|Proteomes:UP000268084}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S14-144 {ECO:0000313|EMBL:AZI57810.1,
RC   ECO:0000313|Proteomes:UP000268084};
RA   Da X.;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AZI57810.1, ECO:0000313|Proteomes:UP000268084}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S14-144 {ECO:0000313|EMBL:AZI57810.1,
RC   ECO:0000313|Proteomes:UP000268084};
RA   Peng F.;
RT   "Nakamurella antarcticus sp. nov., isolated from Antarctica South Shetland
RT   Islands soil.";
RL   Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Poorly processive, error-prone DNA polymerase involved in
CC       untargeted mutagenesis. Copies undamaged DNA at stalled replication
CC       forks, which arise in vivo from mismatched or misaligned primer ends.
CC       These misaligned primers can be extended by PolIV. Exhibits no 3'-5'
CC       exonuclease (proofreading) activity. May be involved in translesional
CC       synthesis, in conjunction with the beta clamp from PolIII.
CC       {ECO:0000256|ARBA:ARBA00025589}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC       {ECO:0000256|ARBA:ARBA00010945}.
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DR   EMBL; CP034170; AZI57810.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3G8ZKS4; -.
DR   KEGG; nak:EH165_06260; -.
DR   OrthoDB; 5244088at2; -.
DR   Proteomes; UP000268084; Chromosome.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd03468; PolY_like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.1170.60; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001126; UmuC.
DR   PANTHER; PTHR35369:SF2; BLR3025 PROTEIN; 1.
DR   PANTHER; PTHR35369; BLR3025 PROTEIN-RELATED; 1.
DR   Pfam; PF00817; IMS; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000268084}.
FT   DOMAIN          40..154
FT                   /note="UmuC"
FT                   /evidence="ECO:0000259|Pfam:PF00817"
FT   REGION          420..446
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   537 AA;  57433 MW;  D85ACD68D207015A CRC64;
     MNAEISRTRT LVVWCPDWPV VTALKQAGKH PSAAAAVFLA NRVRACTAAA RSEGVSIGQR
     RREAQSRCPE LVVLHADADR DAREFEAVTV LVESLAPGVE VLRPGMIACP ARGPARFFGS
     EQGAAENIID AVESLGVECR IGVADALSPA VLAARHSRII PVGESARFCG DLPIRELAAE
     SAIAPPERKE LVNLLQRLGI TTFAAFADLP ESKVATRFGA DAVVAHRLAQ GKAERSVSRR
     HIPTDLTIEQ VCDPPLERVD TAAFAARALA ERFHQGLASA GLACTRLTIS ATTERGQELS
     RTWRCAAPLT PAATADRVRW QLDGWLTASR TVVSNSGSSD LGGPGAITML TLHPVEAVAA
     GHIQHGLWGS SGEDDQRAGW ALARIQGLLG PESVLSPLAS GGRNLSQRVE LIPWGQERVP
     TKDPAAPWPG RLSAPSPTRI TVSTPPRDQQ ISLLDTHGDT VRVTPRGMLS AEPSWCSAAT
     GKVSRIIGWA GPWLLDERWW EKRKDPVLAR LQVSLATGPP LLLALSQVGW IVEGTYD
//