ID A0A3G8ZPY1_9ACTN Unreviewed; 219 AA.
AC A0A3G8ZPY1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Manganese transport regulator {ECO:0000256|ARBA:ARBA00032593};
GN ORFNames=EH165_02070 {ECO:0000313|EMBL:AZI59333.1};
OS Nakamurella antarctica.
OC Bacteria; Actinomycetota; Actinomycetes; Nakamurellales; Nakamurellaceae;
OC Nakamurella.
OX NCBI_TaxID=1902245 {ECO:0000313|EMBL:AZI59333.1, ECO:0000313|Proteomes:UP000268084};
RN [1] {ECO:0000313|EMBL:AZI59333.1, ECO:0000313|Proteomes:UP000268084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S14-144 {ECO:0000313|EMBL:AZI59333.1,
RC ECO:0000313|Proteomes:UP000268084};
RA Da X.;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AZI59333.1, ECO:0000313|Proteomes:UP000268084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S14-144 {ECO:0000313|EMBL:AZI59333.1,
RC ECO:0000313|Proteomes:UP000268084};
RA Peng F.;
RT "Nakamurella antarcticus sp. nov., isolated from Antarctica South Shetland
RT Islands soil.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DtxR/MntR family.
CC {ECO:0000256|ARBA:ARBA00007871}.
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DR EMBL; CP034170; AZI59333.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3G8ZPY1; -.
DR KEGG; nak:EH165_02070; -.
DR OrthoDB; 9791355at2; -.
DR Proteomes; UP000268084; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR Gene3D; 2.30.30.90; -; 1.
DR Gene3D; 1.10.60.10; Iron dependent repressor, metal binding and dimerisation domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR007167; Fe-transptr_FeoA.
DR InterPro; IPR001367; Fe_dep_repressor.
DR InterPro; IPR036421; Fe_dep_repressor_sf.
DR InterPro; IPR038157; FeoA_core_dom.
DR InterPro; IPR022687; HTH_DTXR.
DR InterPro; IPR022689; Iron_dep_repressor.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR33238; IRON (METAL) DEPENDENT REPRESSOR, DTXR FAMILY; 1.
DR PANTHER; PTHR33238:SF7; TRANSCRIPTIONAL REGULATOR MNTR; 1.
DR Pfam; PF02742; Fe_dep_repr_C; 1.
DR Pfam; PF01325; Fe_dep_repress; 1.
DR Pfam; PF04023; FeoA; 1.
DR SMART; SM00899; FeoA; 1.
DR SMART; SM00529; HTH_DTXR; 1.
DR SUPFAM; SSF47979; Iron-dependent repressor protein, dimerization domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50944; HTH_DTXR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000268084};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..59
FT /note="HTH dtxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50944"
SQ SEQUENCE 219 AA; 23827 MW; B8FF8E522C84CB53 CRC64;
MQDYLKAICN AGEWDDTPVT TSVIASRVGV SASSASEMVR KLALLGYLRH EPYGAVELTP
PGRAIALRVV RRHRLVETFL VAELGYTWDE VHDDADILEH AISDRMLARM DAKLGFPRRD
PHGDPIPGAD GTMEIPPAKQ LSALQPGDSG LVVRISDDEP EMLRYFQEKK IVLDAHIEVL
ARLPFGAGTS MRIGGAGGDS LDLGDQAAEA IWLGTTQSR
//
