ID A0A3G9J3H4_9ACTN Unreviewed; 357 AA.
AC A0A3G9J3H4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Cystathionine gamma-synthase {ECO:0000313|EMBL:BBH18178.1};
GN ORFNames=Back2_24650 {ECO:0000313|EMBL:BBH18178.1};
OS Nocardioides baekrokdamisoli.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=1804624 {ECO:0000313|EMBL:BBH18178.1, ECO:0000313|Proteomes:UP000271573};
RN [1] {ECO:0000313|EMBL:BBH18178.1, ECO:0000313|Proteomes:UP000271573}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 39748 {ECO:0000313|EMBL:BBH18178.1,
RC ECO:0000313|Proteomes:UP000271573};
RA Kang S.W., Lee K.C., Kim K.K., Kim J.S., Kim D.S., Ko S.H., Yang S.H.,
RA Shin Y.K., Lee J.S.;
RT "Complete genome sequence of Nocardioides baekrokdamisoli strain KCTC
RT 39748.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|RuleBase:RU362118}.
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DR EMBL; AP019307; BBH18178.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3G9J3H4; -.
DR KEGG; nbe:Back2_24650; -.
DR OrthoDB; 9780685at2; -.
DR Proteomes; UP000271573; Chromosome.
DR GO; GO:0016846; F:carbon-sulfur lyase activity; IEA:UniProt.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11808:SF93; CYSTATHIONINE GAMMA-LYASE-RELATED; 1.
DR PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000271573}.
FT COILED 238..265
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 191
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 357 AA; 38515 MW; F6ADB5D0CC26784B CRC64;
MEQLSPATQV VHAGRPLKVP DAPLNTPITM ASTYVGGGEF EYGRWTNPTW TAFEEALGTL
EGGHALAYSS GQAATAVLLD LVSDSTVVCG QAYSGTIGQL ADLQLRERLR SKLVDITDLD
EVAAAVDDDD VALLWIESPT NPGMEVADLP ALIKLAHDAG VRVVVDNTFA TPLLQRPLEL
GADIVVHSVT KFLAGHSDVT MGAVVVSDEE LFKVLKGRRD LLGAIPGPFE AWLALRGLRT
LALRVERASA NARELASRLR EAGVEVRDPG FGAMLAIVMP TAEAGEWVER RVRLWTHATS
LGGVESTLER RRRWVSESPD VPEGLLRLSV GIEDVEDLWA DLDQAISAKG EEISDER
//
