ID A0A3L6RLY2_PANMI Unreviewed; 622 AA.
AC A0A3L6RLY2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=EVI5-like protein {ECO:0000313|EMBL:RLN05574.1};
GN ORFNames=C2845_PM13G12120 {ECO:0000313|EMBL:RLN05574.1};
OS Panicum miliaceum (Proso millet) (Broomcorn millet).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Panicinae; Panicum.
OX NCBI_TaxID=4540 {ECO:0000313|EMBL:RLN05574.1, ECO:0000313|Proteomes:UP000275267};
RN [1] {ECO:0000313|Proteomes:UP000275267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30683860; DOI=10.1038/s41467-019-08409-5;
RA Zou C., Miki D., Li D., Tang Q., Xiao L., Rajput S., Deng P., Jia W.,
RA Huang R., Zhang M., Sun Y., Hu J., Fu X., Schnable P.S., Li F., Zhang H.,
RA Feng B., Zhu X., Liu R., Schnable J.C., Zhu J.-K., Zhang H.;
RT "The genome of broomcorn millet.";
RL Nat. Commun. 10:436-436(2019).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the mitochondrial pyruvate carrier (MPC) (TC
CC 2.A.105) family. {ECO:0000256|ARBA:ARBA00006416}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLN05574.1}.
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DR EMBL; PQIB02000008; RLN05574.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L6RLY2; -.
DR STRING; 4540.A0A3L6RLY2; -.
DR Proteomes; UP000275267; Chromosome 13.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006850; P:mitochondrial pyruvate transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.10.750; Ypt/Rab-GAP domain of gyp1p, domain 1; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR005336; MPC.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR PANTHER; PTHR47219:SF9; GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B; 1.
DR PANTHER; PTHR47219; RAB GTPASE-ACTIVATING PROTEIN 1-LIKE; 1.
DR Pfam; PF03650; MPC; 1.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000275267};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 165..356
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT REGION 106..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 622 AA; 68876 MW; F150E44E5368B0BA CRC64;
MPCSGLLRLL GAAAGGNGGL GAAGAPDSDG AGGGFIRTGR PRVDLRGDFV WLRISRIAGI
RVWADTIFDI WAACSNILTE MDKKKAIDDT EPGPAPSRAV DRFGFIKPEQ SGSPDGLPKG
RSIHEREREE RRIRKWRKMI GVGGSDWKHY VRRNPHVVKR RIRKGIPDCL RGLVWQLISG
SRDLLLMNPG VYETLVIYET SASELEIIRD ISRTFPSHIF FQQRHGPGQR SLYNILKAYS
VYDRDVGYVQ GMGFLAGLLL LYMSEEDAFW LLVALLKGAV HAPMEGLYQA GLPLVQQYLS
QFEKLVMEHM PKLGQHFVEE MINPSMYASQ WFITVFSYSF PFHLTLRVWD VFLYEGIKVV
FQVGLALLRF CHDDLVKLPF EKLLHALRNF PEEATDPDVL LPIAFTFKVS SRLEELQKEY
QKGPEGSSET SSIKRHQALI SKTMSRGRIV LGQSPSPSSS RRDPLLSLVA GSPAGLDPPA
MSAAFKAFLN SPVGPKTTHF WGPVSNWGII LASVADTKKP PEMISGNMTG GRRNTTLGTA
AVSTRPTELL MLVFFCSFVR VFCSLRQVRM DGAAPELLPH GNPQLQRVRP ALPAVSLGQG
SGVPGEEERA GGPRVVKMAL NL
//
