ID   A0A3L6RTX4_PANMI        Unreviewed;       781 AA.
AC   A0A3L6RTX4;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE            EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN   ORFNames=C2845_PM11G28730 {ECO:0000313|EMBL:RLN09238.1};
OS   Panicum miliaceum (Proso millet) (Broomcorn millet).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Panicodae; Paniceae; Panicinae; Panicum.
OX   NCBI_TaxID=4540 {ECO:0000313|EMBL:RLN09238.1, ECO:0000313|Proteomes:UP000275267};
RN   [1] {ECO:0000313|Proteomes:UP000275267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=30683860; DOI=10.1038/s41467-019-08409-5;
RA   Zou C., Miki D., Li D., Tang Q., Xiao L., Rajput S., Deng P., Jia W.,
RA   Huang R., Zhang M., Sun Y., Hu J., Fu X., Schnable P.S., Li F., Zhang H.,
RA   Feng B., Zhu X., Liu R., Schnable J.C., Zhu J.-K., Zhang H.;
RT   "The genome of broomcorn millet.";
RL   Nat. Commun. 10:436-436(2019).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RLN09238.1}.
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DR   EMBL; PQIB02000007; RLN09238.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3L6RTX4; -.
DR   STRING; 4540.A0A3L6RTX4; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000275267; Chromosome 11.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   CDD; cd16664; RING-Ubox_PUB; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR045210; RING-Ubox_PUB.
DR   InterPro; IPR003613; Ubox_domain.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR23315:SF243; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR   PANTHER; PTHR23315; U BOX DOMAIN-CONTAINING; 1.
DR   Pfam; PF04564; U-box; 1.
DR   SMART; SM00504; Ubox; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS51698; U_BOX; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000275267}.
FT   DOMAIN          260..334
FT                   /note="U-box"
FT                   /evidence="ECO:0000259|PROSITE:PS51698"
FT   REGION          210..238
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        216..238
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   781 AA;  86955 MW;  D8739BDE0752BCDF CRC64;
     MGISQRKSCP KVHSSMCNEL TMMLDKVSSI LPSIEAARPG CKAGIQELCN LYNVVEKGKL
     ITLHCVECSK LYLAITGETI VARCEKIRDS LRRSLFLIQN MVPPALANQI VEVHDDLQDV
     KFVLDPLEEE AGKAILQMLR QSDASEELEL ETFLQAASKL DLTSPKALLI ERRAIKKLLD
     KVNGNDPKKE GVLKFFLYLI KKYGKSIRSE TGERNENLQS ESQSLTPSTT SSDASPPEKC
     YTPTDFQIYE DHNSMSGAAT PPAEFCCPIS TKLMHDPVII TSGQTYEREN IERWFNEGYD
     TCPRTQIKLE NFSMIPNTCM RDLICNWCKE HGFTLSNFVP PSESAYSYSP EQLHGYSMSS
     LHNVSVPLIA GKDNSFVIDH SNTSFALSDA SYVSNASHAR DMEDSKDISQ FSWNADYQKY
     LSFHNFNRDM FLRFFHELSM LPLELQDKSI KDLKNVLDYE NGVSHIMVSK GFVEAFLEFL
     RNDAGSQSVQ AQKAGFQFFL AFLSNSRAKV PSMNEEAFHL ITSFLDSELK GEALLTLHEL
     VQHLSSPRSH VMASVVTPPL FKILASEDTE GLELALKIIC ELSCDADIRS SLVSMGIISK
     LVPIFSEGSF VECCLEILRN LCDMEEAAAR IARTDRCLAS VAEYLDTGSP KEREHAVVIL
     LEICSRSIED CLLVMKEGVI PALVDLSVNG TEEAKSCSIK LLHLLRDMRR SDQFTNSCSQ
     EVAATDAVED APDNSVHKQP SFLGCYGTFA ACKISRYSSS LTGGKLAVVY SAVSKIPAKP
     E
//