ID A0A3L6S4K4_PANMI Unreviewed; 794 AA.
AC A0A3L6S4K4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=CSC1-like protein RXW8 {ECO:0000313|EMBL:RLN15564.1};
GN ORFNames=C2845_PM02G00030 {ECO:0000313|EMBL:RLN15564.1};
OS Panicum miliaceum (Proso millet) (Broomcorn millet).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Panicinae; Panicum.
OX NCBI_TaxID=4540 {ECO:0000313|EMBL:RLN15564.1, ECO:0000313|Proteomes:UP000275267};
RN [1] {ECO:0000313|Proteomes:UP000275267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30683860; DOI=10.1038/s41467-019-08409-5;
RA Zou C., Miki D., Li D., Tang Q., Xiao L., Rajput S., Deng P., Jia W.,
RA Huang R., Zhang M., Sun Y., Hu J., Fu X., Schnable P.S., Li F., Zhang H.,
RA Feng B., Zhu X., Liu R., Schnable J.C., Zhu J.-K., Zhang H.;
RT "The genome of broomcorn millet.";
RL Nat. Commun. 10:436-436(2019).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLN15564.1}.
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DR EMBL; PQIB02000005; RLN15564.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L6S4K4; -.
DR Proteomes; UP000275267; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR PANTHER; PTHR13018:SF99; TO DEHYDRATION PROTEIN, PUTATIVE, EXPRESSED-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000275267};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 548..580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 601..623
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 629..647
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..166
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 187..344
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 355..621
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 715..746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 727..742
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 794 AA; 90860 MW; 1F768CE2E742B79C CRC64;
MEFSALLTSA GINIAVCILF LSLYSVLRKQ PHNFSVYFGR RLAEEKFQKQ DDYFSFERLL
PTAGWIVKAY WCTEEEIRQV AGLDSVVFLR LFIFSIRIFS ITSLVCVFGV LPVNYHGKEI
THDHIPTEQL NVFTIANIIQ ESQKLWVHCI ALYIITISAC ILLFNEYKYI SRKRLAHITG
SSPNPGHFTV LVRSIPKSDN ELLDDTIRNF FVNYHGSSYL SHQMILRKGH FQRFVDRAER
AYRKFMRVRL SVSERNGRSS MSRCGVCGVR ASSFQIYRNK FIEAKKADLT NPEVVDAQKN
CPGALVFFKT RYAAVVASRV LQSSNPMLWV TDLAPEPRDV YWSNLWIPYK QIWLRKLATL
AASVVFMFVF IIPVAFVQSM MQLEQLRKMF PNLRGLLNKS FFARVVTGYL PSVVLLLSLY
TVPPLMMLFS SVEGSISRSG RKRSACLKIL FFTVWNVFFV NVLSGSVLNQ LNVFTRPKDM
PTMLAELVPK QATFFITYVL TSGWASLCSE ILQVYNLVYN FFSKCIFCCH QNTEYVYSFP
YHTEVPKVLL FILLGFTFAI MAPLILPFLL VYFCLGYLVY RNQILNVYYP KYEMGGKLWP
IMHNTIVFSL VLMQVIALGV FTIKHSPVAT GFTILLLVAT VLFNEYCRHR FSRIFEAYSA
QVIEQRNPSP PSGDPGRGSI YLSSLRRHGR RLSELPWPLR FCVARQDVIE LDRDDEQSGR
MQEIHQHLQD AYSQTPPGAE GSSRSGGQVP IELILEDPAQ EASESSQELC DTVQEVSEAH
EHSIEEAAGK AHCV
//
