ID A0A3L6SFQ4_PANMI Unreviewed; 391 AA.
AC A0A3L6SFQ4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=11-beta-hydroxysteroid dehydrogenase 1B-like {ECO:0008006|Google:ProtNLM};
GN ORFNames=C2845_PM02G08420 {ECO:0000313|EMBL:RLN19818.1};
OS Panicum miliaceum (Proso millet) (Broomcorn millet).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Panicinae; Panicum.
OX NCBI_TaxID=4540 {ECO:0000313|EMBL:RLN19818.1, ECO:0000313|Proteomes:UP000275267};
RN [1] {ECO:0000313|Proteomes:UP000275267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30683860; DOI=10.1038/s41467-019-08409-5;
RA Zou C., Miki D., Li D., Tang Q., Xiao L., Rajput S., Deng P., Jia W.,
RA Huang R., Zhang M., Sun Y., Hu J., Fu X., Schnable P.S., Li F., Zhang H.,
RA Feng B., Zhu X., Liu R., Schnable J.C., Zhu J.-K., Zhang H.;
RT "The genome of broomcorn millet.";
RL Nat. Commun. 10:436-436(2019).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLN19818.1}.
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DR EMBL; PQIB02000005; RLN19818.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L6SFQ4; -.
DR STRING; 4540.A0A3L6SFQ4; -.
DR Proteomes; UP000275267; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR43391:SF76; 11-BETA-HYDROXYSTEROID DEHYDROGENASE-LIKE 6; 1.
DR PANTHER; PTHR43391; RETINOL DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00106; adh_short; 1.
DR PRINTS; PR00081; GDHRDH.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000275267};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 391 AA; 42373 MW; ADB7A54B651F6983 CRC64;
MKENEGGQGQ TSNAGRSGDS QYNCRRRPVA SIGRRRSQAG TRAMELYLLL HSVVMHAIAA
LVILVYIPVC VPARLLARAL VRPRRKEDLR GKVVLITGAS SGIGEELAYQ YAREGAYLAL
VARRKQALKS VAAAALERGA PDVLVLPADV ADPEQSRRAV EETVAHFGKL NHLVANAGIW
SSCSFDQVTN IAAFTKLMDV NFWGSVYPTY YALPHLKASR GKLVVSCSAA GTVATSRMAF
YNASKAAQLR FYETLRTELG SEVGITILTA GYVESEITKG KGVQKGGEVA VDEDARDAQI
GVFPVGRVET LCEVALDAVR SGDWYVTWPS MYRPMQLVAC LAPEVLSWVS YALYKEEAAK
GSRPLGQRIL EATGAKTLFP PSLLHPVVKT D
//
