ID A0A3L6SPK4_PANMI Unreviewed; 1088 AA.
AC A0A3L6SPK4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=E3 ubiquitin-protein ligase HERC1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=C2845_PM07G19920 {ECO:0000313|EMBL:RLN24582.1};
OS Panicum miliaceum (Proso millet) (Broomcorn millet).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Panicinae; Panicum.
OX NCBI_TaxID=4540 {ECO:0000313|EMBL:RLN24582.1, ECO:0000313|Proteomes:UP000275267};
RN [1] {ECO:0000313|Proteomes:UP000275267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30683860; DOI=10.1038/s41467-019-08409-5;
RA Zou C., Miki D., Li D., Tang Q., Xiao L., Rajput S., Deng P., Jia W.,
RA Huang R., Zhang M., Sun Y., Hu J., Fu X., Schnable P.S., Li F., Zhang H.,
RA Feng B., Zhu X., Liu R., Schnable J.C., Zhu J.-K., Zhang H.;
RT "The genome of broomcorn millet.";
RL Nat. Commun. 10:436-436(2019).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLN24582.1}.
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DR EMBL; PQIB02000004; RLN24582.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L6SPK4; -.
DR STRING; 4540.A0A3L6SPK4; -.
DR Proteomes; UP000275267; Chromosome 7.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00065; FYVE_like_SF; 1.
DR CDD; cd13365; PH_PLC_plant-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR013591; Brevis_radix_dom.
DR InterPro; IPR027988; BRX_N.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22870:SF456; OS01G0700200 PROTEIN; 1.
DR PANTHER; PTHR22870; REGULATOR OF CHROMOSOME CONDENSATION; 1.
DR Pfam; PF08381; BRX; 1.
DR Pfam; PF13713; BRX_N; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF16457; PH_12; 1.
DR Pfam; PF00415; RCC1; 6.
DR PRINTS; PR00633; RCCNDNSATION.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR PROSITE; PS51514; BRX; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS00626; RCC1_2; 2.
DR PROSITE; PS50012; RCC1_3; 6.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000275267};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 45..149
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REPEAT 309..360
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 361..415
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 416..467
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 478..529
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 530..581
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 582..633
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 638..700
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 1013..1068
FT /note="BRX"
FT /evidence="ECO:0000259|PROSITE:PS51514"
FT REGION 16..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 706..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 861..880
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1066..1088
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 716..730
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1088 AA; 118461 MW; 3F9261A7422077FF CRC64;
MRAATCQDAD LRGGLVETAS SQLGPRPRPV IPPEKGPRQT EALITLKKGS KLIKYSRKGK
PKIRTFRLSS DETTLIWYSH KREKFLRLSS VSKVIPGQRT AVFRRFLHPE KDYLSFSLIY
KNGQRSLDLV CKDQAEVEVW FSALEGLISS CRKSSVDEHK DRVSFSDEVS YYQDSHSYDS
TLDIASSISR SFHTAGYCKT DSFSLRRSDA GSDRANMIRT SGADSTRLSI SSAPSSSSQG
SGTDDIESLG DVYVWGEVWT DVAPSDGNTS SSCSKVDVLI PKPLESDVVL DVNQIVCGSR
HVALTTRQGE VFTWGEEVGG RLGHGTDADI SRPKLVESIS ATIVDFISCG EFHTCAISAA
GDLFNWGDGS YHAGLLGYDT GASHWLPKRV SGPLEGLQVL SVACGSWHSA LITSSGKLHT
FGDGRFGVLG HGNRESVAYP KEVEALNGFR TVKVACGVWH SAAIVEATVH IGMNVVSKKL
YTWGDGDKNR LGHGDKEARL IPTCVQALLE HNFHQLACGQ NMTVALATSG HVYTMGSADN
GQLGNPKSDG KQPCLVKDKL GNELVEEISC GASHVAVLTS RSEVYTWGMG ANGRLGHGDV
NDKKTPTIVE ALKDRHVKSI SCGSNFTTCI CIHKWVSGAD QSVCTGCRQA FGFTRKRHNC
YNCGLVHCHA CSSRKVLKAA LAPTPGKPHR VCDSCFLKLK NADTNTNNVS KRNAPTRRSI
DSREKPEIRP SKLVATPSAE PVKYMEVKSA KSDLKAAESI VKASQASAML QLGFAAQFGA
LQPMGMSPAL AMSPAMPAFS LAPPSPSPYT KKTKSPPAAA IPQSSKIDFD HLQKSNELLN
QELLKLQSQV DDLKQKCEAQ HEQLQKSDKN AKSVASMAAE ESTKRNAAVE FVKFLDNELK
GIVDKLPGDA VDSIKALQVQ THSLLKEQSS HPSELMNTVE RDHLNLSSGG SARYDLASHK
SGGVGYLTMS QDGRPASGSA ISITSESPSH CFMENSAKAH GDFAPKHGTH GEVQLIEQFE
PGVYVTLIQL KDGTKVFKRV RFSKRRFAEN QAEEWWRENQ ERVFRKYSHP TQSAHGNTTS
SHEDEHHP
//
