ID A0A3L6TFV5_PANMI Unreviewed; 1116 AA.
AC A0A3L6TFV5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Putative disease resistance protein RGA3 {ECO:0000313|EMBL:RLN36183.1};
GN ORFNames=C2845_PM03G07030 {ECO:0000313|EMBL:RLN36183.1};
OS Panicum miliaceum (Proso millet) (Broomcorn millet).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Panicinae; Panicum.
OX NCBI_TaxID=4540 {ECO:0000313|EMBL:RLN36183.1, ECO:0000313|Proteomes:UP000275267};
RN [1] {ECO:0000313|Proteomes:UP000275267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30683860; DOI=10.1038/s41467-019-08409-5;
RA Zou C., Miki D., Li D., Tang Q., Xiao L., Rajput S., Deng P., Jia W.,
RA Huang R., Zhang M., Sun Y., Hu J., Fu X., Schnable P.S., Li F., Zhang H.,
RA Feng B., Zhu X., Liu R., Schnable J.C., Zhu J.-K., Zhang H.;
RT "The genome of broomcorn millet.";
RL Nat. Commun. 10:436-436(2019).
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLN36183.1}.
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DR EMBL; PQIB02000002; RLN36183.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L6TFV5; -.
DR STRING; 4540.A0A3L6TFV5; -.
DR Proteomes; UP000275267; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF864; OS09G0313500 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000275267};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1068..1087
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1094..1115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..92
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 163..379
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT COILED 108..135
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1116 AA; 127082 MW; 494859C54872E6F6 CRC64;
MMIATAALPA ASRSVAALLE GEGGVPADEL RRLDRKLTKA RGLAADAEAK EGRDAGARAW
LRELRDALYE LGDAADDFRI AGARRQLEGR RSLRHWFTLP SSTERNQYKT LKTSISNLNA
KMKDILQKGS DLELEAINHE GQNGRSEFAW EAVLDDFTLG DIENEKNELI DVLTDRKNTK
KVVTIVGCSG IGKTTLARKI HEDHHTRNAF SIVVWVNVFS GFNDTGLLSA IVRAAGGNPR
AEENRVQLEA MLAAILKGKR FLLVLDDVRN HQIYENSLEA YWHLCGHGSR ILITTRDESV
VMKVKDAHIH RVKKLSFQDC WSLLCSNACL DESVHGNTLR NIGISIIQKC NKLPMAVKII
GAVLRTKERT QEAWQRVQES EGWLFKDLQD YVHGLTEAIF LGYHDLPLHL KQCFIYLSLI
PEGFVIRQQF VSQLWISEGL IEERDNCSLE KIAEEYYREL LSRNLLQPET GNDDTTRCRM
HNQIRSFLQF FAKDKFFSGD LKTTINGNSS EALRHMWIRS NVPTTVEEMG TVASLKTVIL
YKTPLGNRSL DKLFKGLKYL QVLDLAGTEI TYVPRTMESL YHLRLLNLSL TRIADLPESI
ESLTNLMFLG LRYCNWLHNL PNGIGKLQNL RNLDLRGTNL HQVLPSLVNL KQLSTLHGFV
VNRKPKREDD PTGWPLEDIK SLDALRSLQI LRLERVSDSS RVQEAMLEAK SHLKELELCC
SNDDRQSDIR EENARTLKDI FDRLSPPQCL KSLKIVSYYG KLFPDWLPNL SNLQRLVLTD
CKFCEHLPNL GQLTELKFLT ITSCSKLVTI KQVRTHTSQA FPKLERLHLR DMANLQSWIG
FEPDDMPSLA EFRLENCPKL HYLPSGIKNS GVLRSMQLRH VESLQIVEDL PVLKELVLQA
CSGLERISNL PSLEVLVVLG CSWLKDITGV HPLRHVRIVD RELRELPGWF ATNASMLQTF
TIVGAAELLQ RLLPNGEDWE IIRHIRKVYA NLPDESPFFT YTKSSADFHV DQRIGERVNP
HVLPGAGIPH EALSISLDNS VVRTSRIGAL RVQVRRISTL KTAIRRYLVL YLIMTIIVMQ
VLSYLLQNRT NREIWLVQTL VIFFTTVLLL LLVFLE
//
