ID   A0A3L6TJB3_PANMI        Unreviewed;       416 AA.
AC   A0A3L6TJB3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN   ORFNames=C2845_PM01G00110 {ECO:0000313|EMBL:RLN40369.1};
OS   Panicum miliaceum (Proso millet) (Broomcorn millet).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Panicodae; Paniceae; Panicinae; Panicum.
OX   NCBI_TaxID=4540 {ECO:0000313|EMBL:RLN40369.1, ECO:0000313|Proteomes:UP000275267};
RN   [1] {ECO:0000313|Proteomes:UP000275267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=30683860; DOI=10.1038/s41467-019-08409-5;
RA   Zou C., Miki D., Li D., Tang Q., Xiao L., Rajput S., Deng P., Jia W.,
RA   Huang R., Zhang M., Sun Y., Hu J., Fu X., Schnable P.S., Li F., Zhang H.,
RA   Feng B., Zhu X., Liu R., Schnable J.C., Zhu J.-K., Zhang H.;
RT   "The genome of broomcorn millet.";
RL   Nat. Commun. 10:436-436(2019).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RLN40369.1}.
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DR   EMBL; PQIB02000001; RLN40369.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3L6TJB3; -.
DR   STRING; 4540.A0A3L6TJB3; -.
DR   Proteomes; UP000275267; Chromosome 1.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003960; F:NADPH:quinone reductase activity; IEA:InterPro.
DR   CDD; cd05286; QOR2; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 2.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR047618; QOR-like.
DR   PANTHER; PTHR48106; QUINONE OXIDOREDUCTASE PIG3-RELATED; 1.
DR   PANTHER; PTHR48106:SF13; QUINONE OXIDOREDUCTASE-RELATED; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000275267}.
FT   DOMAIN          73..410
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   416 AA;  44412 MW;  2C4A49F3C9DE2127 CRC64;
     MTTRTATRWV SSSSCFPRRR PRLLHLLPSF AVAVTTPSRS RPGPSPSSSR LRLRCSGDRI
     MVKAKAIRVH ELGGPEVMRW EEVELGDPKE GEIRIKTTAI GVNFIDVYFR KGVYAAPALP
     FTPGSPINSF SSDCVKFLLT KFNSSTNNIG MEAVGVVTAV GPGLTGRKVG DVVAYAGNPM
     GSYAQEQILP ASVAVPVPPS VDHKQAASVM LKGMTAHVLL RRVFKVESGH TVLVHAAAGG
     VGSLLCQWAN ALGATVIGTV SNEEKAAQAT QDGCHHVIIY TKEDVVARVK EITSGKGVNV
     VYDSVGKDTY KASVECLASR GFLVSFGQSS GKPDPIPMSD LASKSLFLTR PSLMHYTATR
     DELLESAGEV FANVANGVLR VRVNHTYLLS EAARAHADLE GRKTSGSIVL IPDTDS
//