ID   A0A3L6ZV37_9MICO        Unreviewed;       397 AA.
AC   A0A3L6ZV37;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Thiolase family protein {ECO:0000313|EMBL:RLP71421.1};
GN   ORFNames=D9V29_08750 {ECO:0000313|EMBL:RLP71421.1};
OS   Mycetocola manganoxydans.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Mycetocola.
OX   NCBI_TaxID=699879 {ECO:0000313|EMBL:RLP71421.1, ECO:0000313|Proteomes:UP000270299};
RN   [1] {ECO:0000313|EMBL:RLP71421.1, ECO:0000313|Proteomes:UP000270299}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCTCC AB209002 {ECO:0000313|EMBL:RLP71421.1,
RC   ECO:0000313|Proteomes:UP000270299};
RA   Li J.;
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC       {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RLP71421.1}.
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DR   EMBL; RCUV01000008; RLP71421.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3L6ZV37; -.
DR   OrthoDB; 3204099at2; -.
DR   Proteomes; UP000270299; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   CDD; cd00751; thiolase; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR002155; Thiolase.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR020617; Thiolase_C.
DR   InterPro; IPR020613; Thiolase_CS.
DR   InterPro; IPR020616; Thiolase_N.
DR   NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR   PANTHER; PTHR43365; BLR7806 PROTEIN; 1.
DR   PANTHER; PTHR43365:SF1; STEROID 3-KETOACYL-COA THIOLASE FADA6; 1.
DR   Pfam; PF02803; Thiolase_C; 1.
DR   Pfam; PF00108; Thiolase_N; 1.
DR   PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
DR   PROSITE; PS00737; THIOLASE_2; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW   Reference proteome {ECO:0000313|Proteomes:UP000270299};
KW   Transferase {ECO:0000256|RuleBase:RU003557}.
FT   DOMAIN          5..267
FT                   /note="Thiolase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00108"
FT   DOMAIN          274..396
FT                   /note="Thiolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02803"
FT   ACT_SITE        91
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT   ACT_SITE        353
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT   ACT_SITE        383
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ   SEQUENCE   397 AA;  41531 MW;  A529BCB7E7BEB78C CRC64;
     MSRAVIIDAI RTPSGRGKPG GGLSEIHPVD LLAQVLQQLV ERTGIDPARI DDVIAGCVTQ
     AGRQSVNIAR NAVLAAGLPE SVPGTTVDRQ CGSSQQAAQF AAQAIMAGTS DIVIACGVEQ
     MSRQPIGYAT LGEDAYGQGV RERYPDGLVH QGISAELIAA RWKLSRSDLD AYAAQSHRRA
     ASAIDRGLFV PEVVPVNVPG ADGSSTRFGV DETVRRGTTA DGLAGLSPAF RTDEYAERFP
     DIGWNITAGN ASPLTDGASA ALIMSEEKAE ELGLTPLARF VGFAQVGSDP IEMLTGVIPA
     TQRLLERTGV SIDDIDVFEV NEAFASVPLA WQREFDVDAS KLNPWGGAIA LGHPLGASGT
     RILATLVNAL NTGGGRYGLQ TMCEGGGMAN ATLIERI
//