ID   A0A3L7JY42_9BACI        Unreviewed;       411 AA.
AC   A0A3L7JY42;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Insulinase family protein {ECO:0000313|EMBL:RLQ95696.1};
GN   ORFNames=D9X91_08705 {ECO:0000313|EMBL:RLQ95696.1};
OS   Falsibacillus albus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Falsibacillus.
OX   NCBI_TaxID=2478915 {ECO:0000313|EMBL:RLQ95696.1, ECO:0000313|Proteomes:UP000276770};
RN   [1] {ECO:0000313|EMBL:RLQ95696.1, ECO:0000313|Proteomes:UP000276770}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GY 10110 {ECO:0000313|EMBL:RLQ95696.1,
RC   ECO:0000313|Proteomes:UP000276770};
RA   Shi S.;
RT   "Falsibacillus sp. genome draft.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RLQ95696.1}.
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DR   EMBL; RCVZ01000005; RLQ95696.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3L7JY42; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000276770; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR11851:SF149; GH01077P; 1.
DR   PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000276770}.
FT   DOMAIN          12..159
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          166..338
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   411 AA;  46531 MW;  F3DF370F143E020D CRC64;
     MIKKYTCQNG VRIVLEEIPT VRSVAIGIWI GTGSRDETPE NNGISHFLEH MFFKGTENRG
     AREIAEAFDA IGGQVNAFTS KEYTCYYAKV LDNHSEMALD ILSDMFFNST FDQEELKKEK
     NVVFEEIKMY EDTPDDIVHD LLSKAAYQSH PLGYPILGTE ETLDTFDQNK LKEYMHNMYT
     PDKVVISIAG NINEEFIRTV EKKFGTYKGG NRAIFEKEPE FHFNQLARKK DTEQAHLCLG
     FEGLQIGHRD VYSLIVLNNI LGGSMSSRLF QEVREKRGLA YSVFSYHTSY KDSGMVTIYG
     GTGAKQMDQL FDTVQETLAL LKKDGITEKE LLNSKEQLKG NLMLSLESTN SRMSRNGKNE
     LLLGRHRSLD EIVDEVDSVT IKGVNELSNR IFTDLYSLSL IGPNGDLPKG I
//