ID A0A3L8P5W5_9ACTN Unreviewed; 398 AA.
AC A0A3L8P5W5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Precorrin-6y C5,15-methyltransferase (Decarboxylating) subunit CbiE {ECO:0000313|EMBL:RLV50372.1};
GN Name=cbiE {ECO:0000313|EMBL:RLV50372.1};
GN ORFNames=D9V37_04805 {ECO:0000313|EMBL:RLV50372.1};
OS Nocardioides mangrovicus.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=2478913 {ECO:0000313|EMBL:RLV50372.1, ECO:0000313|Proteomes:UP000281708};
RN [1] {ECO:0000313|EMBL:RLV50372.1, ECO:0000313|Proteomes:UP000281708}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4Q3S-7 {ECO:0000313|EMBL:RLV50372.1,
RC ECO:0000313|Proteomes:UP000281708};
RA Li F.;
RT "Marmoricola sp. 4Q3S-7 whole genome shotgun sequence.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005879}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLV50372.1}.
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DR EMBL; RDBE01000002; RLV50372.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L8P5W5; -.
DR OrthoDB; 9787825at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000281708; Unassembled WGS sequence.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11644; Precorrin-6Y-MT; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR012818; CbiE.
DR InterPro; IPR006365; Cbl_synth_CobL.
DR InterPro; IPR014008; Cbl_synth_MTase_CbiT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR02467; CbiE; 1.
DR NCBIfam; TIGR02469; CbiT; 1.
DR PANTHER; PTHR43182; COBALT-PRECORRIN-6B C(15)-METHYLTRANSFERASE (DECARBOXYLATING); 1.
DR PANTHER; PTHR43182:SF1; COBALT-PRECORRIN-7 C(5)-METHYLTRANSFERASE; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR PIRSF; PIRSF036428; CobL; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:RLV50372.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000281708};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:RLV50372.1}.
FT DOMAIN 6..182
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 398 AA; 41982 MW; B7C2B0C28FD0D6BC CRC64;
MPEPLVTVVG IGAEGWSSVP EVAREAIVRA DVLIGSSRQL GLLQEGGQVR VPWPSPLREG
LPALLAEHAG RRVVALASGD PMLHGVGTTL VELLGADRVT VHPAVSSVAL ACARLGWSTD
STVVLRDHRT LPRELAPGRR ILVLSADETT PAEVARILQD ASAGDSVVTV LADLGSAGES
RIAKTPHLRF SEWPEVPRLN VVAVEVGTTA QVWSFGAAGL PDAAYEHDGQ LTKRDVRASA
LARLAPMPGQ LLWDVGAGAG SVGIEWLRAH PSCRAVAVEA DPERADRIGR NAARLGVPVL
RVVTGTAPEA LDGLPTPDAV FVGGGATREV VDACLGARRI VVHGVTLETE RLLAELHAEH
GGELTRLSVE HAAPLGSYTG WTPARTVTQW SLERSWER
//
