ID A0A3L8Q675_CHLGU Unreviewed; 125 AA.
AC A0A3L8Q675;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Vesicle-associated membrane protein 8 {ECO:0000256|ARBA:ARBA00039271};
DE AltName: Full=Endobrevin {ECO:0000256|ARBA:ARBA00042205};
DE Flags: Fragment;
GN ORFNames=DV515_00018914 {ECO:0000313|EMBL:RLV62816.1};
OS Chloebia gouldiae (Gouldian finch) (Erythrura gouldiae).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Passeridae;
OC Chloebia.
OX NCBI_TaxID=44316 {ECO:0000313|EMBL:RLV62816.1, ECO:0000313|Proteomes:UP000276834};
RN [1] {ECO:0000313|EMBL:RLV62816.1, ECO:0000313|Proteomes:UP000276834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Red01 {ECO:0000313|EMBL:RLV62816.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:RLV62816.1};
RX PubMed=30282656;
RA Toomey M.B., Marques C.I., Andrade P., Araujo P.M., Sabatino S.,
RA Gazda M.A., Afonso S., Lopes R.J., Corbo J.C., Carneiro M.;
RT "A non-coding region near Follistatin controls head colour polymorphism in
RT the Gouldian finch.";
RL Proc. R. Soc. B 285:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004521};
CC Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004521}.
CC Early endosome membrane {ECO:0000256|ARBA:ARBA00037832}; Single-pass
CC type IV membrane protein {ECO:0000256|ARBA:ARBA00037832}. Endosome
CC membrane {ECO:0000256|ARBA:ARBA00037867}; Single-pass type IV membrane
CC protein {ECO:0000256|ARBA:ARBA00037867}. Late endosome membrane
CC {ECO:0000256|ARBA:ARBA00037845}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00037845}. Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00037863}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00037863}. Membrane
CC {ECO:0000256|ARBA:ARBA00004211}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004211}. Zymogen granule membrane
CC {ECO:0000256|ARBA:ARBA00037825}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00037825}.
CC -!- SIMILARITY: Belongs to the synaptobrevin family.
CC {ECO:0000256|ARBA:ARBA00008025}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLV62816.1}.
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DR EMBL; QUSF01005165; RLV62816.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L8Q675; -.
DR STRING; 44316.ENSEGOP00005013078; -.
DR Proteomes; UP000276834; Unassembled WGS sequence.
DR GO; GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042589; C:zymogen granule membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd15868; R-SNARE_VAMP8; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR InterPro; IPR001388; Synaptobrevin-like.
DR InterPro; IPR016444; Synaptobrevin/VAMP.
DR InterPro; IPR042855; V_SNARE_CC.
DR PANTHER; PTHR45701; SYNAPTOBREVIN FAMILY MEMBER; 1.
DR PANTHER; PTHR45701:SF7; VESICLE-ASSOCIATED MEMBRANE PROTEIN 8; 1.
DR Pfam; PF00957; Synaptobrevin; 1.
DR PRINTS; PR00219; SYNAPTOBREVN.
DR SUPFAM; SSF58038; SNARE fusion complex; 1.
DR PROSITE; PS50892; V_SNARE; 1.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PROSITE-
KW ProRule:PRU00290}; Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000276834};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 98..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..96
FT /note="V-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50892"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RLV62816.1"
SQ SEQUENCE 125 AA; 13337 MW; 904DC5585369C370 CRC64;
GGVQGAPPDP HPVPQAGVPA GSPADVAADG TGGEGRVRAL QREVQGVTTI MTQNVERILA
RGENLEQLHS KSQDLEATSE HFRTTSQKMA RRYWWKNVKL LVILGLVGVI VLILIILLAT
GTIPT
//
