ID A0A3L8RTQ8_CHLGU Unreviewed; 315 AA.
AC A0A3L8RTQ8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE RecName: Full=TNFR-Cys domain-containing protein {ECO:0000259|PROSITE:PS50050};
GN ORFNames=DV515_00016069 {ECO:0000313|EMBL:RLV85331.1};
OS Chloebia gouldiae (Gouldian finch) (Erythrura gouldiae).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Passeridae;
OC Chloebia.
OX NCBI_TaxID=44316 {ECO:0000313|EMBL:RLV85331.1, ECO:0000313|Proteomes:UP000276834};
RN [1] {ECO:0000313|EMBL:RLV85331.1, ECO:0000313|Proteomes:UP000276834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Red01 {ECO:0000313|EMBL:RLV85331.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:RLV85331.1};
RX PubMed=30282656;
RA Toomey M.B., Marques C.I., Andrade P., Araujo P.M., Sabatino S.,
RA Gazda M.A., Afonso S., Lopes R.J., Corbo J.C., Carneiro M.;
RT "A non-coding region near Follistatin controls head colour polymorphism in
RT the Gouldian finch.";
RL Proc. R. Soc. B 285:0-0(2018).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLV85331.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QUSF01000250; RLV85331.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L8RTQ8; -.
DR STRING; 44316.ENSEGOP00005016250; -.
DR Proteomes; UP000276834; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005031; F:tumor necrosis factor receptor activity; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR CDD; cd13406; TNFRSF4; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR020445; TNFR_4.
DR InterPro; IPR034022; TNFRSF4_N.
DR PANTHER; PTHR47881; TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 4; 1.
DR PANTHER; PTHR47881:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 4; 1.
DR Pfam; PF00020; TNFR_c6; 3.
DR SMART; SM00208; TNFR; 3.
DR SUPFAM; SSF57586; TNF receptor-like; 2.
DR PROSITE; PS00652; TNFR_NGFR_1; 1.
DR PROSITE; PS50050; TNFR_NGFR_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000276834};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..315
FT /note="TNFR-Cys domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018273943"
FT TRANSMEM 250..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 27..61
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 27..61
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT DOMAIN 63..104
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 63..104
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT REGION 177..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 40..53
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 43..61
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 315 AA; 33828 MW; 86426C105F6BD4AF CRC64;
MALPRLAWGL AALCWLLAAL AAARGPQCPE RQYRFRERCC SECGPGERMR SRCTASADTV
CSPCQDGYFS SQHHHGLCHS CTVCNAWKGS VEVKPCEKTS DRICACRAGF QPAGGTPGIP
VGKECSRCPA GTFSRGRNEN CHPWTNCSTL GKSTLQAGTG TEDAQCGTEF PENRRPFPTE
FLENGAPSAT EFPESRDPSA TEFPENRAPS ATEFLGKRGS LPTEFPGNGS SPREVPMVCR
DPGVPAEPGW GSLSLLLLCL LLLLVSGISI LLLMVQAVRK TSRNGPARSG QHKGGSCRIP
IQEEQIDSNS SLIKN
//
