ID A0A3L8RUH5_CHLGU Unreviewed; 790 AA.
AC A0A3L8RUH5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=G6PE protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DV515_00015676 {ECO:0000313|EMBL:RLV87468.1};
OS Chloebia gouldiae (Gouldian finch) (Erythrura gouldiae).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Passeridae;
OC Chloebia.
OX NCBI_TaxID=44316 {ECO:0000313|EMBL:RLV87468.1, ECO:0000313|Proteomes:UP000276834};
RN [1] {ECO:0000313|EMBL:RLV87468.1, ECO:0000313|Proteomes:UP000276834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Red01 {ECO:0000313|EMBL:RLV87468.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:RLV87468.1};
RX PubMed=30282656;
RA Toomey M.B., Marques C.I., Andrade P., Araujo P.M., Sabatino S.,
RA Gazda M.A., Afonso S., Lopes R.J., Corbo J.C., Carneiro M.;
RT "A non-coding region near Follistatin controls head colour polymorphism in
RT the Gouldian finch.";
RL Proc. R. Soc. B 285:0-0(2018).
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway.
CC {ECO:0000256|ARBA:ARBA00004959}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLV87468.1}.
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DR EMBL; QUSF01000200; RLV87468.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L8RUH5; -.
DR STRING; 44316.ENSEGOP00005015740; -.
DR Ensembl; ENSEGOT00005018168; ENSEGOP00005015740; ENSEGOG00005012753.
DR OMA; YCPQSGT; -.
DR UniPathway; UPA00115; -.
DR Proteomes; UP000276834; Unassembled WGS sequence.
DR GO; GO:0017057; F:6-phosphogluconolactonase activity; IEA:InterPro.
DR GO; GO:0004345; F:glucose-6-phosphate dehydrogenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR CDD; cd01400; 6PGL; 1.
DR Gene3D; 3.40.50.1360; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR005900; 6-phosphogluconolactonase_DevB.
DR InterPro; IPR001282; G6P_DH.
DR InterPro; IPR019796; G6P_DH_AS.
DR InterPro; IPR022675; G6P_DH_C.
DR InterPro; IPR022674; G6P_DH_NAD-bd.
DR InterPro; IPR006148; Glc/Gal-6P_isomerase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR NCBIfam; TIGR01198; pgl; 1.
DR PANTHER; PTHR23429:SF7; GDH_6PGL ENDOPLASMIC BIFUNCTIONAL PROTEIN; 1.
DR PANTHER; PTHR23429; GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD; 1.
DR Pfam; PF02781; G6PD_C; 1.
DR Pfam; PF00479; G6PD_N; 1.
DR Pfam; PF01182; Glucosamine_iso; 1.
DR PRINTS; PR00079; G6PDHDRGNASE.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
DR PROSITE; PS00069; G6P_DEHYDROGENASE; 1.
PE 4: Predicted;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00022526};
KW Glucose metabolism {ECO:0000256|ARBA:ARBA00022526};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000276834};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..790
FT /note="G6PE protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018013391"
FT DOMAIN 29..211
FT /note="Glucose-6-phosphate dehydrogenase NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF00479"
FT DOMAIN 217..507
FT /note="Glucose-6-phosphate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02781"
FT DOMAIN 559..781
FT /note="Glucosamine/galactosamine-6-phosphate isomerase"
FT /evidence="ECO:0000259|Pfam:PF01182"
FT BINDING 208
FT /ligand="substrate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10005"
SQ SEQUENCE 790 AA; 88061 MW; 78273AD626AC9A88 CRC64;
MLGRVLCTVL FVGALPSPAG ASQGHISVVL LGANGDLAKK YLWQGLFQLY MDQVSSGHSF
TFHGAALTAL EPGQRLMFDV LKKLSCPPDE APNRCAVLKD QFLKLSQYHQ LGTAEDYTAL
NRDIETLLGQ EGLKEAGRIF YFSVPPFAYT EIARHVNSSC RPRAGAWLRV VLEKPFGHDL
HSAQQLAAEL AGFFSEEEMY RVDHYLGKQA VAHILPFRDQ NRQFLGPIWN RHHVERVEVV
LKETVDAKGR TRFYEQYGVI RDVLQNHLTE ALLFLVMELP ANASSAQELV QHKLQAFQSL
WGLQRSSAVL GQYQAYDSQV QEELQEARGY VSTTPTFAGV LIHSQSPRWE GVPFLLTSGK
ALDERVGYAR VLFKNKAYCP QSGTLRDAGH SQCKPKQIIF HFGHGALDAP AVLVSRNLFQ
PVMPKDSWKE AGARSDLHIF GQPLSDFYMY SPVKERDAYS VVISNIYHGR KDFFITVEHL
LASWAFWTPL LDSTSRQPPR LYPGGVENQQ LLDFEMVPGG VAFTLAEPAE LLNPGGQTPS
DFRAIQSKFR QSPLVSGWAE ELIARLASDV EEAAVRSVAR SGRFHLALSG GSSPVGLFQR
LARQHYGFPW QQSHVWLVDE RCVPLTDSES NFQGLHRHLL QHVRVPYFNI HPMPVHLNRR
LCVEEDGGAQ LYAKDIVALV ANASFDLVLL GVGTDGHTAS LFPRSENGLE GAATVVLTES
PVKPHQRMSL SLPLINRARQ VFVLVLGKGK HDITTLLSRV GHEPRKWPIS GVSPSSGQLV
WYVDYEALLG
//
