ID A0A3L8RVU7_CHLGU Unreviewed; 1651 AA.
AC A0A3L8RVU7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Ras-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DV515_00015297 {ECO:0000313|EMBL:RLV88778.1};
OS Chloebia gouldiae (Gouldian finch) (Erythrura gouldiae).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Passeridae;
OC Chloebia.
OX NCBI_TaxID=44316 {ECO:0000313|EMBL:RLV88778.1, ECO:0000313|Proteomes:UP000276834};
RN [1] {ECO:0000313|EMBL:RLV88778.1, ECO:0000313|Proteomes:UP000276834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Red01 {ECO:0000313|EMBL:RLV88778.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:RLV88778.1};
RX PubMed=30282656;
RA Toomey M.B., Marques C.I., Andrade P., Araujo P.M., Sabatino S.,
RA Gazda M.A., Afonso S., Lopes R.J., Corbo J.C., Carneiro M.;
RT "A non-coding region near Follistatin controls head colour polymorphism in
RT the Gouldian finch.";
RL Proc. R. Soc. B 285:0-0(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLV88778.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QUSF01000170; RLV88778.1; -; Genomic_DNA.
DR STRING; 44316.ENSEGOP00005011466; -.
DR Proteomes; UP000276834; Unassembled WGS sequence.
DR GO; GO:0120025; C:plasma membrane bounded cell projection; IEA:UniProt.
DR CDD; cd12207; RasGAP_IQGAP3; 1.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR000593; RasGAP_C.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR001202; WW_dom.
DR PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR PANTHER; PTHR14149:SF10; RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP3; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF00612; IQ; 3.
DR Pfam; PF00616; RasGAP; 1.
DR Pfam; PF03836; RasGAP_C; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM00015; IQ; 4.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF143885; RGC domain-like; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS50096; IQ; 4.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000276834}.
FT DOMAIN 14..129
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 696..729
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 1018..1251
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT COILED 138..165
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1466..1533
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1651 AA; 187334 MW; F7128E2A6494013D CRC64;
MDEQRRQNVA YQYLCHLEEA KRWMEACLGE GLPPPTELEE TLRNGVLLAK LGHCFAPAIV
PLKKIYDPEQ TRYKTAGLHF RHTDNINYWR DAMSHVGLPS IFHPETTDIY DKKNMPRVVY
CIHALSFYLF KLGLAPPIQD LYGKVNFTEE EINNMKQELE KYGLQLPAFS KIGGILANEL
SVDEAAVHAA VLAINEAVDR GVVAQTMETL HNPHAMLLGL RQELADAYQE VLHQAKLEKG
SNARNRVIPE GEDVYDWCLT QAEIQGNINK VNVRGALEEL DNALERQDVL ALHCALQDPI
LALRCIRRDN LELYLEQLSS DREEKALELG YLELLEQEEV QAGILTANRR DEKERASECL
GKLLLQVLLP SASQELWACW QPVPETGHSH LLQPPCASPP VCPSVLQAVG RINAAVRQGV
PAETLEALMD PAAQLPDVHA PAASLYQHQL ALLQNQHPRG ELAQEELFVA VEMLSAVALV
NQALDARNPK RLQSSLVSPA LGLSGAEDAN AQRYFDDLLQ LKGQLRKAGA EFLSWNDIQD
SITSTNSSVQ DENNRVRALC LVNEALLQAD PEKTLAALLL LAPALPDLAL PTALRYHDVL
SRARRQKVQA TEDNGAVLGW EEIQEGVCQA NQDTVAARRM ALGIAAINQA IKEGKASQTL
RVLCNPDVAL CGVVNACADT YQEQLAALMA TKRPAGSMKL SWIRHRLLDG AEYYLNLQTL
EGSWQCPRNG SFNTTHLSRE EMQSVITRVT LAHERECLWA SSVAVVVRLQ ARLRGFLVRR
RFAARRHILR EQRPAAIRIQ ACWRGYRQRR AYLDRLHYLK SNTEAAIKAA VRMWQARRKY
QERLRYFRQN IKAVIKIQAF VRANKARGDY RMLVHTKSPP LGIVRRFIHL LEQSQHDFWE
ESEVLRLQEE VVKRIRASRQ LESDLDLMDI KIGLLVKNRI TLQEVVSHCK KLTKKNKEQL
SEMMSMDKQK GLKTLSKEKR QKLEAYQHLF YLLQTQPVYL ARLIFQMPQN KSTKFMESVI
FTLYNYASNP REAYLLLQLF KVALQEEIRS KVDHVHDILT GNATVIRLVV SFYRNVRGQN
ALRHILAGPV QEVLQDKALS IHTDPVDIYK AWINQTESQS GHRSKLPYEV SPEQALSHPE
VQRRLDISIR NLLAVTDKFV SAITSSVDKI PYGMRYMAKI LRMSLAEKFP KAPAEEVDKI
VGNLLYYRFM NPAVVAPDGF DIVDVSAGAA LRPDQRRSLG SIAKVLQHAA AHRPFQGESA
HLCGLNQYLE HTHNKFRRFI SAACCVPEPE ERFDMDEYSE MVAVAKPVIY ITVGELINTH
KLLLEHQDSI TSHHSDPLHE LLEDLDELPT VQSLVGESVA SLGDSGAEQV LSQLSRTEIS
LTLTNKLVPV ASSEESDSRS LLLSTKQMLV DLIQCQPGDS LTEILWTPAS QHEEAAHEHL
VCQRALRDAQ PSAQLRRHPS LAAKARLSME EKKRKVIRNL RRLESLGLAH SASQYQELID
ELAKDIRNQR RHRQQRRREL LKLRQTLEGL DAKTLFYEEQ IDYYNQYIKT CLDNLAAGNK
GSGKSKKLPS LHYTAAQLFR NVVFDIIPCE ESGRFQVKAK FMGIDMEHFQ LHYQDLLQLQ
YEGVAVMKMF DKAKVNVNLL IFLLNKKFFK K
//
