ID A0A3L8SA79_CHLGU Unreviewed; 1498 AA.
AC A0A3L8SA79;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Caskin-2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=DV515_00009949 {ECO:0000313|EMBL:RLV99214.1};
OS Chloebia gouldiae (Gouldian finch) (Erythrura gouldiae).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Passeridae;
OC Chloebia.
OX NCBI_TaxID=44316 {ECO:0000313|EMBL:RLV99214.1, ECO:0000313|Proteomes:UP000276834};
RN [1] {ECO:0000313|EMBL:RLV99214.1, ECO:0000313|Proteomes:UP000276834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Red01 {ECO:0000313|EMBL:RLV99214.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:RLV99214.1};
RX PubMed=30282656;
RA Toomey M.B., Marques C.I., Andrade P., Araujo P.M., Sabatino S.,
RA Gazda M.A., Afonso S., Lopes R.J., Corbo J.C., Carneiro M.;
RT "A non-coding region near Follistatin controls head colour polymorphism in
RT the Gouldian finch.";
RL Proc. R. Soc. B 285:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLV99214.1}.
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DR EMBL; QUSF01000033; RLV99214.1; -; Genomic_DNA.
DR STRING; 44316.ENSEGOP00005014944; -.
DR Proteomes; UP000276834; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd09497; SAM_caskin1_2_repeat1; 1.
DR CDD; cd09498; SAM_caskin1_2_repeat2; 1.
DR CDD; cd12063; SH3_Caskin2; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 2.
DR InterPro; IPR033635; ANKS1/Caskin.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR032232; Caskin1-CID.
DR InterPro; IPR035497; Caskin1/2_SAM_1.
DR InterPro; IPR035498; Caskin1/2_SAM_2.
DR InterPro; IPR035499; Caskin2_SH3.
DR InterPro; IPR032117; Caskin_C.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR24174; ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR24174:SF18; CASKIN-2; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF16907; Caskin-Pro-rich; 1.
DR Pfam; PF16632; Caskin-tail; 1.
DR Pfam; PF16600; Caskin1-CID; 1.
DR Pfam; PF00536; SAM_1; 2.
DR Pfam; PF07653; SH3_2; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 6.
DR SMART; SM00454; SAM; 2.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 2.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 5.
DR PROSITE; PS50105; SAM_DOMAIN; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000276834};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT REPEAT 27..59
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 60..92
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 93..125
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 167..199
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 199..231
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 260..326
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 488..551
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 557..621
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 336..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 683..823
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 847..1219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1439..1466
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 344..358
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..746
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 860..889
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 900..930
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 933..949
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1125..1145
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1498 AA; 158692 MW; 324A982D1B7E901A CRC64;
MGQALFCALG ELLGSAKRLN VNYQDADGFS ALHHAALGGS LDLISLLLEA QATVDIKDSN
GMRPLHYAAW QGRVEPVRVL LRAAASVNMA SLDGQIPLHL SAQYGHYEVS EMLLQHQSNP
CLINKAKKTP LDLACEFGRL KVAQLLLNSH LCVALLEGQS KDATDPNYTT PLHLAAKNGH
KEIIRQLLKA GIEINKQTKT GTALHEAALY GKTEVVRLLL EGGVDVNIRN TYNQTALDIV
NQFTTSHASK DIKQLLREAS GILKVRALKD FWNLHDPTAL NVRAGDVITV LEQHPDGRWK
GHIHDAQKGT DRVGYFPPSI AEVISKRTGM VVPRVAPAQQ RQGPPGALPA PPGGLQHLPD
ECPHPAAPSG PAAFGHLTLT RTAPGPDSSA AGDRNSVGSE GSIGSIRSAG SGQSTEGTNG
QSTSILIENA RPLPSTGDNL QQHLLGSEPH NGTSPAGPQG LQTPGSYPPG DRVFSHQFLR
PEQLLEGKDA EAIYNWLREF QLESYTINFL NAGYDVPTIS RMTPEDLTAI GVTKPGHRKK
ISTEIGQLSI AEWLPNYIPA DLMDWLSAIG LPQYHKKLVN NGYDSITIVT DLTWEDLQEI
GINKLGHQKK IMLAVKKLRD LRKSLNQAEA TLARRKIPGS LDIVTIESLE NGECQSPHTL
KMTTFQDSEL SYELQTAMSN SCHDTLGIKS SQGMSRSQES IGVRSRGSGH SQDNVLSRRL
SSPSQESLGS GESSSSSGQS CAPPRSKESP ASLPGRPSPE PYGKLVSPEG LNGFANSGGG
GGSPLKERNL PEGTDQYARP VAQKGAGTPV VTPCTPPQTP SKGTAPYVFM YPHVSLKSPT
APSVLGAEQP KALAHPYPSI SPGQKSSLQT SAQKGFSYLH SQCGPTEPPT AAPTTGEHHN
GGEGLKHKKR SHSLNRYALS DGEHEEEEGA PSSTLGSYAT LTRRPGRSQT PRGCLQAEAK
VTRSQSFAIR AKRKGPPPPP PKRLSSVSSA LAAEADAEQP PSPERQPAAP QDVVDAGATP
SDAGRGRTVK SLAAALEGTP GVSPSKPLLA PKPLHLTQDC LPRADVGEGS HDGSDASSAT
LPNGSRDPFE SGKPRRRTVS EPSAPMTEVA AQGEQEDACS DTEEETKPGV SSSSSQNSSS
ECIPFAEEGN LTIKQRPKPS GHSKADAAVL DMEPGSQPAE PQGSPGKEPA APAVTKEPPV
LEFNLTESDT VKRRPRFRER EPLQAVLKAF SMAGQAEGGG TPTPQYAQAQ AVSIAGPPAS
APAPQPTLAG DAFDDDSVEF RIAEIEKSIL SLEKGMKKAP SPTKASSPTE VVSTAVVRTP
TPGMGVCGAI SKVAVGLPPM LVWEVRRTCA TTYHKSSSFA DVPAKHTSVA STKLVFSGPK
TIYQQVLQPS RHTVAPWAAT EVVPDVIGSL PGPGSLVIET GSKVSAKPLA AAPGATLAQQ
RLEQTNSSLA ATLQAAEKKI TVEEAESHPG TVHSAKNILE DISNMFDDLA DQLDAMLD
//
