ID A0A3L8SE79_CHLGU Unreviewed; 811 AA.
AC A0A3L8SE79;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Interleukin-1 receptor accessory protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DV515_00008718 {ECO:0000313|EMBL:RLW00706.1};
OS Chloebia gouldiae (Gouldian finch) (Erythrura gouldiae).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Passeridae;
OC Chloebia.
OX NCBI_TaxID=44316 {ECO:0000313|EMBL:RLW00706.1, ECO:0000313|Proteomes:UP000276834};
RN [1] {ECO:0000313|EMBL:RLW00706.1, ECO:0000313|Proteomes:UP000276834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Red01 {ECO:0000313|EMBL:RLW00706.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:RLW00706.1};
RX PubMed=30282656;
RA Toomey M.B., Marques C.I., Andrade P., Araujo P.M., Sabatino S.,
RA Gazda M.A., Afonso S., Lopes R.J., Corbo J.C., Carneiro M.;
RT "A non-coding region near Follistatin controls head colour polymorphism in
RT the Gouldian finch.";
RL Proc. R. Soc. B 285:0-0(2018).
CC -!- SIMILARITY: Belongs to the interleukin-1 receptor family.
CC {ECO:0000256|ARBA:ARBA00009752}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLW00706.1}.
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DR EMBL; QUSF01000026; RLW00706.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L8SE79; -.
DR STRING; 44316.ENSEGOP00005007248; -.
DR Proteomes; UP000276834; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0004908; F:interleukin-1 receptor activity; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR CDD; cd20992; Ig1_IL1R_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 2.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR015621; IL-1_rcpt_fam.
DR InterPro; IPR004074; IL-1_rcpt_I/II-typ.
DR InterPro; IPR041416; IL-1RAcP-like_ig.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11890:SF20; INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN; 1.
DR PANTHER; PTHR11890; INTERLEUKIN-1 RECEPTOR FAMILY MEMBER; 1.
DR Pfam; PF18452; Ig_6; 1.
DR Pfam; PF01582; TIR; 2.
DR PRINTS; PR01536; INTRLKN1R12F.
DR PRINTS; PR01537; INTRLKN1R1F.
DR SMART; SM00409; IG; 3.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
DR PROSITE; PS50104; TIR; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Inflammatory response {ECO:0000256|ARBA:ARBA00023198};
KW Membrane {ECO:0000256|SAM:Phobius}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000276834};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..811
FT /note="Interleukin-1 receptor accessory protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018052933"
FT TRANSMEM 375..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 40..127
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 246..360
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 415..558
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 684..728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..698
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 811 AA; 91875 MW; DB8B2103A0DE25B0 CRC64;
MKMVSVLLVS LWLSMLTLGR GSERCDDWGV DTMKQIQIYD GEPAKIKCPL FETFLKYNYS
TAHSAGLTLI WYRIAQDRDL EEPINYRLPD NHISKDKDTL WFWPALLNDT GNYTCMLRNT
TYCSKVAFPL EVVPKDQHSC VSHSIKPTEE MFYLEHANQK ITCPDIDGFY PASVTPTVKW
YLNCNSVDGF YERYPQGPKL VIGIVRSAYK GNYTCIVTFK DHGRTYNLTR TIKMKVVGSP
NKALPPQFTS PNEKVVYELE AGDDGPFFAG DDLILPCEVF FTFLKDSRTE VWWTIDGRNT
DDITDPKIKL TQSEITRDFE DKTLVRTLTV AKATAEELKR NYTCHARNAK GEERSQAVVR
MKVVAPKYTV ELACGLGATI LLVVVLIVIY HVYWLEMVLF YRAHFGTDET ILDGKEYDVY
VSYARNAEEE EFVLLTLRGV LENEFGYKLC IFDRDSLPGG IVTDETLSFI QKSRRLLVVL
SPNYVLQGTQ ALLELKAGLE NMASKGNIKV ILVQYKAIKK SKVKELKQAK AALNVIKWKG
EKSKFPKGRF WKQLQVEMPV KKISRSLSLD GLMHIPEKYT TEAVFDFIQR SRRMIVVLSP
DYLTEKSISL LEFKLGIMCQ NAIATKLIVV EYRPLQCTHP SILQLKESVS FVTWKGEKSK
RSGSQFWKAL RLALPLRSLS ASAGWNESCS SQSDISLDPV QRRRSRLKGQ PDPRGATPVT
LTQGRAASAS ASKAKQRAKH FLTCRCCGTY CNGGSRHKQR AVAEPRWDGH LCSPARGLQG
RARAEPPPAQ GPALALCHYS DLSNNNDFYV L
//
