ID A0A3L8SKB3_CHLGU Unreviewed; 828 AA.
AC A0A3L8SKB3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=SEC7 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DV515_00007013 {ECO:0000313|EMBL:RLW03028.1};
OS Chloebia gouldiae (Gouldian finch) (Erythrura gouldiae).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Passeridae;
OC Chloebia.
OX NCBI_TaxID=44316 {ECO:0000313|EMBL:RLW03028.1, ECO:0000313|Proteomes:UP000276834};
RN [1] {ECO:0000313|EMBL:RLW03028.1, ECO:0000313|Proteomes:UP000276834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Red01 {ECO:0000313|EMBL:RLW03028.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:RLW03028.1};
RX PubMed=30282656;
RA Toomey M.B., Marques C.I., Andrade P., Araujo P.M., Sabatino S.,
RA Gazda M.A., Afonso S., Lopes R.J., Corbo J.C., Carneiro M.;
RT "A non-coding region near Follistatin controls head colour polymorphism in
RT the Gouldian finch.";
RL Proc. R. Soc. B 285:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Cell projection, ruffle membrane
CC {ECO:0000256|ARBA:ARBA00004632}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLW03028.1}.
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DR EMBL; QUSF01000017; RLW03028.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L8SKB3; -.
DR STRING; 44316.ENSEGOP00005017306; -.
DR Proteomes; UP000276834; Unassembled WGS sequence.
DR GO; GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd13295; PH_EFA6; 1.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041681; PH_9.
DR InterPro; IPR001605; PH_dom-spectrin-type.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR10663:SF329; PH AND SEC7 DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF15410; PH_9; 1.
DR Pfam; PF01369; Sec7; 1.
DR PRINTS; PR00683; SPECTRINPH.
DR SMART; SM00233; PH; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000276834}.
FT DOMAIN 351..518
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT DOMAIN 568..681
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 337..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 709..736
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 16..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..75
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..149
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 828 AA; 91623 MW; 4B44B5933A98A806 CRC64;
MSESSPLPWS AACESEPHSP RSQPSPLAGS DGDEQPSQPA EPASGRASPR HDAQPSREEG
EQRDEHLEAV TEPGERLSER GQGPGAGGQS GRADGAGLPN GVDAAPAAGP ERPQDGDGAG
RSSPQPGDNR GSPGPQAASG ALSKQRWHSV LGSSEALSAD EAEEQFGFAS GDVKLSCSDD
DREHFQFKDI RDGFSSTFEK IVESDLMKGT YYSSLDSLDV LSLTDETDSC VSFEAPLTPL
IQQRAKESPE LLEQKLAAQQ REALHHMAAD KQEQAAAKPV EGDFGSPLRH SITSSRSENV
LSRLSLKSIP NGFHVEGSEE DATKIINSIS DASLKDTLSD SDSDMGSTEQ LDQGSTDTLA
NGCRADSEAA KRLAKRLYNL EGFKRCDVAR QLGKNNEFSK LVAEEYLSFF DFTGLTLDKA
LRTFLKAFPL MGETQERERV LIHFSRRYCQ CNPEESTSED GIHTLTCALM LLNTDLHGHN
IGKKMSCQQF IANLDGLNDG KDFAKDLLKT LYNSIKNEKL EWAIDEDELR KSLSELVDDK
FGASAKKVTR IVDSSNPFLD IPQALNAVTY KHGVLTRKTH ADMDGKRTPR GRRGWKKFYA
VLKGTVLYLQ KDEYKPDKDL SEVDLKNAIR VHHALATKAS DYSKKSNVLK LKTADWRVFL
FQAPSKEEML SWILRINLVA AIFSAPAFPA AICSMKKFCR PLLPSSMTKL CQEEQLRSHE
NKMKQIADEL AEHKLHPVEK SLKSKEAEEY RLKEHYLIFE KSRYETYINL LCMKIKVGTD
DLERIETSFF KVEADDIALR KTHSSPSLSQ GHMSISCKAE KDILEQNT
//
