ID A0A3L8SM17_CHLGU Unreviewed; 1569 AA.
AC A0A3L8SM17;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Canalicular multispecific organic anion transporter 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=DV515_00005916 {ECO:0000313|EMBL:RLW04172.1};
OS Chloebia gouldiae (Gouldian finch) (Erythrura gouldiae).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Passeridae;
OC Chloebia.
OX NCBI_TaxID=44316 {ECO:0000313|EMBL:RLW04172.1, ECO:0000313|Proteomes:UP000276834};
RN [1] {ECO:0000313|EMBL:RLW04172.1, ECO:0000313|Proteomes:UP000276834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Red01 {ECO:0000313|EMBL:RLW04172.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:RLW04172.1};
RX PubMed=30282656;
RA Toomey M.B., Marques C.I., Andrade P., Araujo P.M., Sabatino S.,
RA Gazda M.A., Afonso S., Lopes R.J., Corbo J.C., Carneiro M.;
RT "A non-coding region near Follistatin controls head colour polymorphism in
RT the Gouldian finch.";
RL Proc. R. Soc. B 285:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Early endosome membrane
CC {ECO:0000256|ARBA:ARBA00004146}. Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004608}. Endosome, multivesicular body membrane
CC {ECO:0000256|ARBA:ARBA00004333}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004653}. Late endosome membrane
CC {ECO:0000256|ARBA:ARBA00004414}. Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00004656}. Melanosome membrane
CC {ECO:0000256|ARBA:ARBA00024320}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion outer membrane
CC {ECO:0000256|ARBA:ARBA00004374}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004374}. Secreted, extracellular exosome
CC {ECO:0000256|ARBA:ARBA00004550}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLW04172.1}.
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DR EMBL; QUSF01000014; RLW04172.1; -; Genomic_DNA.
DR STRING; 44316.ENSEGOP00005010140; -.
DR Proteomes; UP000276834; Unassembled WGS sequence.
DR GO; GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0033162; C:melanosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18595; ABC_6TM_MRP1_2_3_6_D1_like; 1.
DR CDD; cd18603; ABC_6TM_MRP1_2_3_6_D2_like; 1.
DR CDD; cd03250; ABCC_MRP_domain1; 1.
DR CDD; cd03244; ABCC_MRP_domain2; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR032410; MTABC_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24223; ATP-BINDING CASSETTE SUB-FAMILY C; 1.
DR PANTHER; PTHR24223:SF176; ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 2; 1.
DR Pfam; PF00664; ABC_membrane; 3.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF16185; MTABC_N; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000276834};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 34..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 476..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 518..535
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 555..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 960..983
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1014..1036
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1095..1126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1146..1166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1237..1257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 336..524
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 612..835
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 970..1288
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1324..1558
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 260..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 299..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 911..939
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..280
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..315
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 924..939
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1569 AA; 174947 MW; CE60290A7FECA23D CRC64;
MSAALEKFCG SVFWNDSYLA RPDADLPVCF QQTVLVWIPL GFFWILAPWQ LLPMCKSRAK
KSSVTKLYII KQVLAALLML TAVAELALAF VDAEQGAVPA VQYTNPSLYI ATWIMVLLVQ
DARRFCLRRD SGVLFCFWIL TLLCGILPFQ SLVRKALQEP ISDLPRFILF FISYGLQLLL
FLVSGFSDIA PETKEIWKKN PEVTASFLSS VTFQWYSSIV FKGYRKPLEI EDVWELKDKD
KTKALYTAFE KNMRTAMQKA RAELEKRKRK KRRQEGDPDH GNSMSKAQSQ DILVLEEKQT
KKKKKKGDNE DSGPPKDYPK GWLMKTLVKT FQQNLLLAVA FKVVHDALVF VSPQLLKLLI
AFVSDEDSFA WQGYLYAILL FLAAVIQSLC LQQHFSLCFQ LGINVRASLI AAIYKKSLTM
SGATRKESTV GETVNLMSAD AQRFMDLANF IHQLWSSPLQ IILSIVFLWG ELGPSVLAGI
ATLVLLLPIN ALLVAKAKTI QERNMKNKDE RMKIMTEILN GIKVSLASFA VYVLVDENNI
LDAQKAFTAI SLFNVLRFPM ATLPMVISSL VQANVSTARL ERYLSGEDLD TSAIHHNPIA
GRQCCAFLRG HLRLGAGWQR CHKRPSCLCS VTLDIMPGSL VAVVGAVGSG KSSLVSAMLG
EMENIRGHIN IQGSLAYVPQ QAWIQNATLK DNIIFGSELD EARYQQVLKA CALLPDLELL
PAGDQTEIGE KGINLSGGQK QRVSLARAVY SNADIYILDD PLSAVDAHVG KYLFEHVLGP
KGLLQKKTRI LVTHSISFLP QVDNIVVLAA GAVSEHGSYS TLLANKGAFS QFLNLYGNQE
EDVSEENTAV VWGGVVSGQC LTLPSLIPLL VAEALAGDEE EADEAVDPCM EERTEDVVTL
TLKREASIHR RKLSRSFSKK STSSQKKAQE EPPKKLKGQQ LIEKEAVETG RVKFSMYLRY
LRAVGLCFTF WIVMGYVGQY AAYVGTNLWL SDWTDDSVRY QNQTYPTERR DLRIGVFGAL
GVSQALFLLF ATMLSARGTV RASRVMHQQL LSNILRAPMS FFDTTPIGRI VNRFAKDIFT
VDETIPMSFR SWISCFMAII STLIVICLAT PFFTVVIIPL SIFYYFVLVR NWALSEASAL
LRAVPWWLLG FVLVTSLCCS FQRFYVSTSR QLRRLDSVTR SPIYSHFGET VSGLSVIRAY
GHQERFLKQN EITMDINQKS VYSWIVSNRW LAIRLEFVGS LVVFFSALLA VIAKGTLEGG
IVGLSVSSAL NVTQTLNWLV RTSSELETNI VAVERVHEYV TVKNEAPWVT KKRPPHGWPS
RGEIQFIDYK VRYRPELDLV LQGITCNIGS TEKVGVVGRT GAGKSSLTNC LFRVLEAAGG
KIIIDNVDIA TIGLHDLRKS LTIIPQDPVL FTGTLRMNLD PFDQYSDEEV WKALELAHLK
TFVQGLPERL LHLVSEAGEN LSVGQRQLVC LARALLRKAK ILILDEATAA VDLETDHLIQ
TTIRSAFADC TVLTIAHRLH TIMDSNRVMV LHAGQIVEFD SPEQLLMKQG IFSAMAKDAG
ITAAESTAL
//
