ID A0A3L8SN64_CHLGU Unreviewed; 479 AA.
AC A0A3L8SN64;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Ras-GEF domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DV515_00006103 {ECO:0000313|EMBL:RLW04218.1};
OS Chloebia gouldiae (Gouldian finch) (Erythrura gouldiae).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Passeridae;
OC Chloebia.
OX NCBI_TaxID=44316 {ECO:0000313|EMBL:RLW04218.1, ECO:0000313|Proteomes:UP000276834};
RN [1] {ECO:0000313|EMBL:RLW04218.1, ECO:0000313|Proteomes:UP000276834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Red01 {ECO:0000313|EMBL:RLW04218.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:RLW04218.1};
RX PubMed=30282656;
RA Toomey M.B., Marques C.I., Andrade P., Araujo P.M., Sabatino S.,
RA Gazda M.A., Afonso S., Lopes R.J., Corbo J.C., Carneiro M.;
RT "A non-coding region near Follistatin controls head colour polymorphism in
RT the Gouldian finch.";
RL Proc. R. Soc. B 285:0-0(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLW04218.1}.
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DR EMBL; QUSF01000014; RLW04218.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L8SN64; -.
DR Ensembl; ENSEGOT00005021209; ENSEGOP00005018479; ENSEGOG00005014773.
DR Proteomes; UP000276834; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF172; RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1A; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000276834}.
FT DOMAIN 37..168
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 212..459
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
SQ SEQUENCE 479 AA; 55553 MW; 853F1BF5D08243D1 CRC64;
MRETMPQTPI FSSMLGSSCS GQVQPDMGER CVDPVYQDGN LVSGSLEALI ERLVPTMDYY
PDRTYIFTFL LSSRVFIHPH ELLAKVGQIC IKQKQQLEMG TEAEKAKLKS FAAKIIQLLK
EWTETFPYDF QDEKSMKELK EIAHRITQCD EENGTVKKII SQMTQNLLMA LSARSQYQEI
REKFRQPVTD KGTILKTKPQ STQKDILSVC CDPLILAQQL TYIELERVSN IYPEDLMQIV
SHMDSLDNHK CRSDVTKTYN LEAYDNWFNC LSMLVATEIC RVVKKKQRTR MVEFFIDVAR
ECFNIGNFNS MMAIISGMNL SPVARLKKTW SKVKTAKFDV LEHHMDPSSN FCNYRTALQG
AAQRSQTANS SREKIVIPVF NLFIKDIYFL HKIHTNRLPN GQINFKKFWE ISRQIHDFLT
WKQVECPFEK DKKIQTYLLT APIYSEEALF IASFESEGPE NHMEKDSWKT LRTTLLNRA
//
