ID A0A3L8SPR2_CHLGU Unreviewed; 1542 AA.
AC A0A3L8SPR2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 13-SEP-2023, entry version 20.
DE RecName: Full=C2 DOCK-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DV515_00004668 {ECO:0000313|EMBL:RLW06004.1};
OS Chloebia gouldiae (Gouldian finch) (Erythrura gouldiae).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Passeridae;
OC Chloebia.
OX NCBI_TaxID=44316 {ECO:0000313|EMBL:RLW06004.1, ECO:0000313|Proteomes:UP000276834};
RN [1] {ECO:0000313|EMBL:RLW06004.1, ECO:0000313|Proteomes:UP000276834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Red01 {ECO:0000313|EMBL:RLW06004.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:RLW06004.1};
RX PubMed=30282656;
RA Toomey M.B., Marques C.I., Andrade P., Araujo P.M., Sabatino S.,
RA Gazda M.A., Afonso S., Lopes R.J., Corbo J.C., Carneiro M.;
RT "A non-coding region near Follistatin controls head colour polymorphism in
RT the Gouldian finch.";
RL Proc. R. Soc. B 285:0-0(2018).
CC -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC ProRule:PRU00983}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLW06004.1}.
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DR EMBL; QUSF01000010; RLW06004.1; -; Genomic_DNA.
DR STRING; 44316.ENSEGOP00005019554; -.
DR Proteomes; UP000276834; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd08696; C2_Dock-C; 1.
DR CDD; cd11703; DHR2_DOCK7; 1.
DR Gene3D; 1.20.58.740; -; 1.
DR Gene3D; 1.25.40.410; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR037808; C2_Dock-C.
DR InterPro; IPR027007; C2_DOCK-type_domain.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR026791; DOCK.
DR InterPro; IPR043161; DOCK_C_lobe_A.
DR InterPro; IPR043162; DOCK_C_lobe_C.
DR InterPro; IPR027357; DOCKER_dom.
DR InterPro; IPR046769; DOCKER_Lobe_A.
DR InterPro; IPR046770; DOCKER_Lobe_B.
DR InterPro; IPR046773; DOCKER_Lobe_C.
DR PANTHER; PTHR23317; DEDICATOR OF CYTOKINESIS DOCK; 1.
DR PANTHER; PTHR23317:SF78; DEDICATOR OF CYTOKINESIS PROTEIN 7; 1.
DR Pfam; PF06920; DHR-2_Lobe_A; 1.
DR Pfam; PF20422; DHR-2_Lobe_B; 1.
DR Pfam; PF20421; DHR-2_Lobe_C; 1.
DR Pfam; PF14429; DOCK-C2; 1.
DR PROSITE; PS51650; C2_DOCK; 1.
DR PROSITE; PS51651; DOCKER; 1.
PE 3: Inferred from homology;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000276834}.
FT DOMAIN 5..171
FT /note="C2 DOCK-type"
FT /evidence="ECO:0000259|PROSITE:PS51650"
FT DOMAIN 1082..1516
FT /note="DOCKER"
FT /evidence="ECO:0000259|PROSITE:PS51651"
FT REGION 335..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..358
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1542 AA; 174795 MW; A889A594C7A2676C CRC64;
MVRPRNLLYV YPQSLNFANR QGSARNITVK VQFMYGEDPS NAMPVIFGKS SCPEFSKEAY
TAVVYHNRSP DFHEEIKIKL PATLTDHHHL LFTFYHVSCQ QKQNTPLETP VGYTWIPMLQ
NGRLKTGQFC LPVSLEKPPQ AYSVLSPEVP LPGMKWVDNH KGVFNVEVVA VSSLHTQDPY
LDKFFALVHA LDEHMFPVRI GDMRIMENNL ENELKSSISA LNSSQLEPVV RFLHLLLDKL
ILLVVRPPVI AGQIVNLGQA SFEAMASIIN RLHKNLDGNQ DQHGRNSLLA SYIYYVFRLP
NTYPNSPSPG PGGLGGSVHY ATMARSAVRP ASLNLNRSRS LSNSNPDISG TPTSPDDEVR
SIIGTKATDR SCNRMSSHTE TSSFLQTLTG RLPTKKLFHE ELALQWVVCS GSVREAALQQ
AWFFFELMVK SMVHHLYFAD KLDAARKNRF PERFMDDVSA LVSTIAGDIV SRFQKDTEMV
ERLNTSLAFF LNDLLSIMDR GFVFTLIKTC YKQVSSKVYT LTNPSNLASL KLDFLRIICS
HEHYVTLNLP CSLLTPPASP SPSVSSATSQ SSGFSTNVQD QKIANMFELS VPFRQQHYLA
GLVLTELAVI LDPDAEGLFG LHKKVINMVH NLLSSHDSDP RYADPQVKAR VAMLYLPLIG
VIMETVPQLY DFTESHNQRG RPSCVTVDDY ESEGGSMINQ TVAMAIAGTS VPQLTRPSSF
LLPSSSGRQH STFSTESSRS LLICLLWVLK NADEGVLQKW FTDLSVLQLN RLLDLLYLCV
SCFEYKGKKV FERMNSLTFK KSKDMRAKLE EAILGSIGAR QEMVRRSRGQ LERSPSGSAF
GSQENLRWRK DMTHWRQNTE KLDKSRAEIE HEALIDGNLA TEANLIILDT LEIVVQTVSV
TESKESILGG VLKVLLHSMA CNQSALYLQH CFATQRALVS KFPELLFEEE TEQCADLCLR
LLRHCSSSVN TIRSHASASL YLLMRQNFEI GNNFARVKMQ VTMSLSSLVG TSQNFNEEFL
RRSLKTILTY AEEDLELRET TFPDQVQDLV FNLHMILSDT VKMKEHQEDP EMLIDLMYRI
AKGYQNSPDL RLTWLQNMAG KHSERSNHAE SAQCLVHSAA LVAEYLSMLE DRKYLPVGCV
TFQNISSNVL EESAVSDDVV SPDEEGICSG KYFTEAGLVG LLEQAAASFS MAGMYEAVNE
VYKVLIPIHE ANRDAKKLST IHGKLQEAFS KIVHQDGKRM FGTYFRVGFY GTKFGDLDEQ
EFVYKEPAIT KLAEISHRLE GFYGERFGED VLEVIKDSNP VDKCKLDPNK AYIQITYVEP
YFDTYEMKDR ITYFDKNYNL RRFMYCTPFT LDGRAHGDLH EQFKRKTILT TSHAFPYIKT
RINVIHKEEI ILTPIEVAIE DMQKKTQELA FATHQDPADP KMLQMVLQGS VGTTVNQGPL
EVAQVFLAEI PNDPKLFRHH NKLRLCFKDF TKRCEDALRK NKSLIGPDQK EYQRELERNY
HRLKEALQPL INRKIPQLYK AVLPVTCHRD SFSRMSLRKM EI
//
