ID A0A3L8SX35_CHLGU Unreviewed; 909 AA.
AC A0A3L8SX35;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=KASH domain-containing protein {ECO:0000259|PROSITE:PS51049};
GN ORFNames=DV515_00001878 {ECO:0000313|EMBL:RLW10416.1};
OS Chloebia gouldiae (Gouldian finch) (Erythrura gouldiae).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Passeridae;
OC Chloebia.
OX NCBI_TaxID=44316 {ECO:0000313|EMBL:RLW10416.1, ECO:0000313|Proteomes:UP000276834};
RN [1] {ECO:0000313|EMBL:RLW10416.1, ECO:0000313|Proteomes:UP000276834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Red01 {ECO:0000313|EMBL:RLW10416.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:RLW10416.1};
RX PubMed=30282656;
RA Toomey M.B., Marques C.I., Andrade P., Araujo P.M., Sabatino S.,
RA Gazda M.A., Afonso S., Lopes R.J., Corbo J.C., Carneiro M.;
RT "A non-coding region near Follistatin controls head colour polymorphism in
RT the Gouldian finch.";
RL Proc. R. Soc. B 285:0-0(2018).
CC -!- SIMILARITY: Belongs to the nesprin family.
CC {ECO:0000256|ARBA:ARBA00008619}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLW10416.1}.
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DR EMBL; QUSF01000004; RLW10416.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L8SX35; -.
DR Proteomes; UP000276834; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0005635; C:nuclear envelope; IEA:UniProt.
DR CDD; cd00176; SPEC; 3.
DR Gene3D; 1.20.58.60; -; 4.
DR InterPro; IPR039906; Anc-1/SYNE1/2-like.
DR InterPro; IPR012315; KASH.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR21524; SPECTRIN REPEAT CONTAINING NUCLEAR ENVELOPE PROTEIN 2; 1.
DR PANTHER; PTHR21524:SF6; SPECTRIN REPEAT-CONTAINING NUCLEAR ENVELOPE PROTEIN 2; 1.
DR Pfam; PF10541; KASH; 1.
DR Pfam; PF00435; Spectrin; 3.
DR SMART; SM01249; KASH; 1.
DR SMART; SM00150; SPEC; 5.
DR SUPFAM; SSF46966; Spectrin repeat; 4.
DR PROSITE; PS51049; KASH; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00385}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000276834};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00385}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT TOPO_DOM 1..858
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT TOPO_DOM 880..909
FT /note="Perinuclear space"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT DOMAIN 850..909
FT /note="KASH"
FT /evidence="ECO:0000259|PROSITE:PS51049"
FT REGION 363..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 432..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 808..843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 719..748
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 378..392
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..523
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 827..843
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 909 AA; 104705 MW; 4A54817EBB9E6268 CRC64;
MPAWSPRRFP PRSLGSAGRG MVLPCGPVKK LKETFTFIQL LDKNMSNLRT WLARIESELS
KPVVYDICDD QEIQKRLAEQ QDLQRDIEQH TAGVESVFNI CDVLLHDSDA CANETECDSI
QQTTRSLDRR WRNICAMSME RRMKIEETWR LWQRFLDDYS RFEDWLKASE NIAARPNSSE
VLYTHAKEEL KKFEAFQRQI HERLTQLELI NKQYRRLARE NRTDSASKLK QMVHEGNQRW
DNLQKRVASI LRRLKHFTNR RDEFEGTRES ILVWLTEMDL QLTNVEHFSK SNFDDKMRQL
NGFQQEITLN TNKIDQLIVF GEQLIQKSEP LDAILIEDEL EELHRYCQEV FGRVARFHQR
LTSRDPGLDD EKDNSENETD QEDSREIQND PWHKKAIAEG PSSAQSLCHL MPPTQGHERS
GCETPVSVDS IPLEWDHTGD VGGSSSHEDD EEATYYSALS GKSVSEAHPW HSPGSPVCRK
HRYNQAEMVG NVLSGPETST PYKPEYVKQL SSASSSSGKE KIPSATMSDE EPQDDQELVN
IAAAEKQSGI IDRWELIQAQ DLRNKLRMKQ KLQQWQQLDS DLSDISAWLD KTEQELEELQ
KVKLPTSMQA LEQKVKKLKD MLKAFDSYKA VLLSANLSSK EFQKADSTEF KELQNRLRKV
NLHWEKATRA LDNWRKGLQQ ALLQCQDFHD QSQKLILWLA SAESRRSEAQ ITAPNADLNA
ILECQKELMQ LEKELLEQQL NVNSLQELTA YLLLKSDGDY IEEEEKVHVI GTKLKQLIEQ
VSHDLKTIQG NLDAKTFLLV PDDLDSGVYN PEEEKSSPAM ALRRTADGRN GSSTRSESHS
QAVQANPRSP SFFYRVLRAA LPLQLFFLLL LLLACMIPSS EEDYSCSQAN NFARSFYPML
RYTNGPPPT
//
