ID A0A3L9DNQ6_9STRE Unreviewed; 384 AA.
AC A0A3L9DNQ6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Class I SAM-dependent RNA methyltransferase {ECO:0000313|EMBL:RLY02951.1};
GN ORFNames=EAF07_06560 {ECO:0000313|EMBL:RLY02951.1};
OS Streptococcus hillyeri.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=2282420 {ECO:0000313|EMBL:RLY02951.1, ECO:0000313|Proteomes:UP000279194};
RN [1] {ECO:0000313|EMBL:RLY02951.1, ECO:0000313|Proteomes:UP000279194}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=28462 {ECO:0000313|EMBL:RLY02951.1,
RC ECO:0000313|Proteomes:UP000279194};
RA Macfadyen A.C., Waller A., Paterson G.K.;
RT "Streptococcus hillyeri sp. nov., isolated from equine tracheal sample.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLY02951.1}.
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DR EMBL; RCVM01000011; RLY02951.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L9DNQ6; -.
DR OrthoDB; 9809404at2; -.
DR Proteomes; UP000279194; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:RLY02951.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000279194};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000313|EMBL:RLY02951.1}.
FT DOMAIN 45..159
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 384 AA; 43074 MW; 154847CAC24652C4 CRC64;
MKEKFNLIAT AAAGLEAVFG REIRNLGIDC QVENGKVRFT GDVKTIAETN LWLRAADRIK
IVVGIFPAKT FEELFQGVFA LDWENYLPLG AAFPISKAKC VKSKLHNEPS VQAITKKAVV
KKLQKHFHRP EGVPLMENGP EFKIEVSILK DVVTVLIDTT GTSLFKRGYR TEKGGAPIKE
NMAAALLQLT NWFPDKPLID PTCGSGTFCI EAAMIGMNIA PGFNRSFAFE AWPWVDKDLV
QSVRDEAESK ANYDIELDIM GCDIDARMVE IAKKNAEEAG LSDVITFKQM RLQDLHTDKI
NGVIVSNPPY GERLLDDNAI TVLYREMGET FAPLKTWSKF ILTSDEAFET KYGSVADKKR
KLYNGTLKVD LYQYYGERVR RQQA
//
