ID A0A3L9YNC8_9RHOB Unreviewed; 1127 AA.
AC A0A3L9YNC8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
DE AltName: Full=DNA 3'-5' helicase II {ECO:0000256|ARBA:ARBA00034923};
GN Name=addA {ECO:0000313|EMBL:RMA44190.1};
GN ORFNames=D9R08_01020 {ECO:0000313|EMBL:RMA44190.1};
OS Rhodophyticola porphyridii.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Rhodophyticola.
OX NCBI_TaxID=1852017 {ECO:0000313|EMBL:RMA44190.1, ECO:0000313|Proteomes:UP000281343};
RN [1] {ECO:0000313|EMBL:RMA44190.1, ECO:0000313|Proteomes:UP000281343}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MA-7-27 {ECO:0000313|EMBL:RMA44190.1,
RC ECO:0000313|Proteomes:UP000281343};
RA Jung H.S., Jeon C.O.;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMA44190.1}.
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DR EMBL; RCNT01000001; RMA44190.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3L9YNC8; -.
DR OrthoDB; 9810135at2; -.
DR Proteomes; UP000281343; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR014151; DNA_helicase_AddA.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR NCBIfam; TIGR02784; addA_alphas; 1.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000281343}.
FT DOMAIN 3..478
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 503..780
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 24..31
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1127 AA; 121582 MW; CFDE06BC91B255D6 CRC64;
MRLDDASRAQ VLAADPGTST WLSANAGSGK TRVLTDRVAR LLLDEVPPER ILCLTYTKAA
ASEMQNRLFR RLGGWAMMPD DDLARALADL GLTAERVTPV LLSRARTLFA RAIETPGGLK
IQTIHSFCGG VLRRFPLEAG VSPGFTEMDE RAQLLLAEDV LADLAEGGDI PAVDGVARYL
SGDDMAGLVR GLLAHRDGVE PPRESDKIFA WFGVDPGLSA ADILRETFLG DEKPLCDRLA
GLLDPKSRAH GKSHRVLSGF DWAAPDLEDL AQIEEVFLTG SGANTPDAAK IGSIGNAQIR
AALGADLPPL EAFMLRLEAA RPRRRAMLSA QKTAALHRFA AAFLPAYDAA KQARGWLDFD
DLIRRMRTLL MAPGVAQWVL FRLDGGIDHI LVDEAQDTAP AQWQIIAKLA EEFASGEGAR
ADTARTVFVV GDKKQSIYSF QGADPSGFDR MRDHFADRLA QIDAPFQSRE LIYSFRSAAP
ILALVDHVAG GAAGAGLGPD VGHRAFKSAL PGRVDIWPHI PKSDTTEPSN WENPVDLLEE
DHHHVRLARR VAEAIGSMLD GKTMIEVEKD GKPSRRAARA GDILILVQRR SDLFHEVIAA
IKAAGLPIAG ADRMRVAAEL AVKDLIALMA FLATPEDDLS LAAVLRSPIL GWSEADLYGL
ANPREGFLWR ALQTRAAEFP QTVALLEDLR DHADFLRPYD LLERVLIRHD ARRNLLARLG
GEAEDGIDAM LGQALAYERM DVPSLTGFVG WLQADDVTIK RDPGSAGNQI RVMSIHGAKG
LESPIVILPD CAQRRAGNRG VTLLEPENGP LIWPLTKTDA PAKVRAALDG MAEAEAEERN
RLLYVAMTRA ESWLIVAAAG ELGKTAAQSW YGTIRESAEA LGAERHPMFG ETGLRLETGD
WMSPGDETPP SDAARPRLPG WALTPVAEEG RMQAARSPSD LGGAKALPSE AAGLAEEAAK
RRGRLIHLLL EYLPGLPQAG WLAASPGILA MEDAVDEVEA SALLEEAARV LNAPGLAAVF
ADDALAEVAL TAWSDTLSVQ MMGVIDRLII REDRVLAVDF KSNAVVPADT AEVPEGLLRQ
MGAYAEMLAP LYPGRRIDTA ILWTRNATLM PLAHGSVMAA LQRAATA
//
