ID   A0A3L9YWS1_9FLAO        Unreviewed;      1026 AA.
AC   A0A3L9YWS1;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=CzcA family heavy metal efflux pump {ECO:0000313|EMBL:RMA64774.1};
GN   ORFNames=BXY75_1655 {ECO:0000313|EMBL:RMA64774.1};
OS   Ulvibacter antarcticus.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Ulvibacter.
OX   NCBI_TaxID=442714 {ECO:0000313|EMBL:RMA64774.1, ECO:0000313|Proteomes:UP000271339};
RN   [1] {ECO:0000313|EMBL:RMA64774.1, ECO:0000313|Proteomes:UP000271339}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23424 {ECO:0000313|EMBL:RMA64774.1,
RC   ECO:0000313|Proteomes:UP000271339};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMA64774.1}.
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DR   EMBL; REFC01000012; RMA64774.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3L9YWS1; -.
DR   OrthoDB; 9758757at2; -.
DR   Proteomes; UP000271339; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   InterPro; IPR004763; CusA-like.
DR   NCBIfam; TIGR00914; 2A0601; 1.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF4; SLR6043 PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000271339};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        336..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        362..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        388..407
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        445..463
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        475..500
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        536..555
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        865..883
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        890..912
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        918..939
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        960..983
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        995..1022
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1026 AA;  112499 MW;  C4E8F18CA802336B CRC64;
     MLNKILSISL QNRLLILLGA AALSVLGVYY ARTMNVDVFP DLTAPTVTIL TEAHGMESEE
     VEKLVTYQLE TALNGSPNVR RIRSSSAAGV SIVWIEFEWG TDIYRARQIV SERIPMVREN
     LPEGIGAPTM APISSIMGEI MLLGVTSDSL SPMELRTLSD WTIRPRLKAI GGIANVVVIG
     GDYKQYQVFA NPEKMKHYDV SLSELVEHVK EANANAPGGV INQYGNQYII KGSGRAYALE
     DLQEAVLKQV NGQTIKIKDV ATVQIGAADK IGDGSLNAKP AVILTISKQP DVNTLELTDR
     LDEAIADLEK TLPKGVNIKS QIFRQSDFID ASISNLNQTL LEGAFFVMII LFIFLMNWRT
     TLISLLAIPI SLLVTIIILK WLGYTINTMS LGGMAIAIGA LVDDAIIDVE NVYKRLRENI
     RKPKEEREST ITVVRDASVE IRSSIIIATL IIIVSFIPLF FLSGMEGRLL QPLGIAFVTS
     VLTSLIVAVT VTPILCSYLL NNEKLLSKQA EGTKVERWLQ KQYGNLLESA TKMPKTIIGT
     TVIAFIISLF VLTQLGRSFL PEFNEGSLVI SVVGPPAMSL EESNKTGKLI ETILLDLPEV
     KVVTRRQGRA ELDEHAQGVN ASEIDVPFVL EDKTKEEFFE EVRNKLSIAP GVNITLGQPI
     AHRIDHMLSG TRANIAIKIF GTDLQRLFEV GKSIEQNIKN IDGLADVAVD QQIEVPQIRI
     KPKRQILSAY GMTVGNLMEQ VDIAFAGEEA GEIYEGQQYF DLVVRYEKPF RDNIENISNT
     LISLPNGGQT TLGELAMVAS VSSPNTINRE DVQRKIVVAA NVQGRDLRGA VEEIKEVVAN
     NVNMPEGYRV QYGGQFESES KASQLLMITA IIAIVVIFLL LYYEFRDVKL AFVVLINLPL
     ALIGGILIVY FTSGIISIAA TIGFISLFGI ATRNGILLVS RYEDLRKEGM KGFQLVKTGA
     LDRLNPILMT AFTTGLALIP LALKGGEPGS EIQSPMAVVI LGGLLTATIL NLVVIPCVYQ
     LVTRKH
//