ID A0A3M0BKA9_9AQUI Unreviewed; 464 AA.
AC A0A3M0BKA9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Do/DeqQ family serine protease {ECO:0000313|EMBL:RMA97790.1};
GN ORFNames=CLV39_0417 {ECO:0000313|EMBL:RMA97790.1};
OS Hydrogenothermus marinus.
OC Bacteria; Aquificota; Aquificae; Aquificales; Hydrogenothermaceae;
OC Hydrogenothermus.
OX NCBI_TaxID=133270 {ECO:0000313|EMBL:RMA97790.1, ECO:0000313|Proteomes:UP000280842};
RN [1] {ECO:0000313|EMBL:RMA97790.1, ECO:0000313|Proteomes:UP000280842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VM1 {ECO:0000313|EMBL:RMA97790.1,
RC ECO:0000313|Proteomes:UP000280842};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
CC -!- SIMILARITY: Belongs to the peptidase S1C family.
CC {ECO:0000256|ARBA:ARBA00010541}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMA97790.1}.
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DR EMBL; REFO01000010; RMA97790.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M0BKA9; -.
DR OrthoDB; 9758917at2; -.
DR Proteomes; UP000280842; Unassembled WGS sequence.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 2.
DR Gene3D; 2.30.42.10; -; 2.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011782; Pept_S1C_Do.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001940; Peptidase_S1C.
DR NCBIfam; TIGR02037; degP_htrA_DO; 1.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:RMA97790.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000280842};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 253..340
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 369..452
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT ACT_SITE 102
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 132
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 212
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
SQ SEQUENCE 464 AA; 50785 MW; 3FBB97C6B403B3DE CRC64;
MKRYFYPVFL ALMLINLSFA SLLEQIEKER VSIVQSVSPG VVTIFTVKEV KVPNPFAGTP
FSDFFGFPGN RNFTQRIEGL GSGFIVKVDK DKKLVYILTN NHVVENATNI KVQFKNRKVL
NGKIVGTDKL SDVAVVSVKF KEGIEKFAEK HTLKLGNSDK LKPGMTVFAI GSPLGFKYTV
TQGIISALNR EIEGHPGEGF IQTDAAINPG NSGGPLINVK GEVVGMNTAI IAGAQGLGFA
VPINQAKWVM DQILKYGKVK RGKLGVVIQP LTPELAKHFG LDYGVIITQV QKGSPAEKAG
LKSGDVIVAV NGHKVKTPND LQKYIMRAGP GAKVDITVYR DGKKITVKAI LGSWEDEYIG
DYEKLEEKYG LKVIDLSPAI REKYQLPKVP YGVLVYGVKY GSVADEAGLR SGDIIISVNQ
KPVKTVSDFW KLIVKAEKRK ASDVLLKVRR GSSIFYTTLP IINE
//
