ID   A0A3M0GAT7_9ACTN        Unreviewed;       896 AA.
AC   A0A3M0GAT7;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=MMPL family transporter {ECO:0000313|EMBL:RMB61417.1};
GN   ORFNames=EAX62_01810 {ECO:0000313|EMBL:RMB61417.1};
OS   Tessaracoccus antarcticus.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Propionibacteriaceae; Tessaracoccus.
OX   NCBI_TaxID=2479848 {ECO:0000313|EMBL:RMB61417.1, ECO:0000313|Proteomes:UP000275256};
RN   [1] {ECO:0000313|EMBL:RMB61417.1, ECO:0000313|Proteomes:UP000275256}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JDX10 {ECO:0000313|EMBL:RMB61417.1,
RC   ECO:0000313|Proteomes:UP000275256};
RA   Zhou L.Y., Du Z.J.;
RT   "Tessaracoccus antarcticuss sp. nov., isolated from sediment.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMB61417.1}.
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DR   EMBL; REFW01000001; RMB61417.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M0GAT7; -.
DR   OrthoDB; 7051771at2; -.
DR   Proteomes; UP000275256; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR001036; Acrflvin-R.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000275256};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        208..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        234..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        273..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        307..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        361..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        525..547
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        559..576
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        596..617
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        638..660
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        672..697
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          205..330
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   896 AA;  94439 MW;  404A6A6406CE680C CRC64;
     MSAQLYALGR WCHRNSWKVI GLWLALLAVT GTTGALVMGD FNDEFRIPGS SSQEALDRLR
     MTFPEGAALS ATAIIIAPEG TDINTLQTAV EAHLDDFTKL GTVESVTSPW NKLVNGLIND
     ADTAAIAQLT LDVDGAPTTE QLKDITDAAD RLQAELPAGS QVHMGGEAYN IELPALSIVE
     GLGLIVALVV LFMVLGSLVA AGLPILTALI GVGVAMALML IITSFASINS TTPLLAVMLG
     LAVGIDYALF ILSRHRDQLR DGMEAEESTG RAVGTAGSAV IFAGLTVFIA LLGLGVAGIP
     FLTVMGVFAA LTVAFAVVIA ITLLPALMGL LGERMRPRVR KPRKVVEGQE PRAPKQKGRA
     FSWWVGVTTK HPIITIVVVV LGLGGLSVPT MDLQLSLPNS GQHEVGAQDR TAYDLVDKYF
     GPGFNGPLII TADIIGSTDP LGLMSSLKAD IEKVDGVASV PLATPNQNAD TGLIQIIPTT
     GADDPATADL VQRLRDKTVE WEDRYGVETA VTGFTAVQID VTDKLAGALL PFGLLVVGLS
     LILLTAVFRS VAVPIKATLG YLFSVGAAFG TTALVFNDGF MRQLINLDEP MPVISFLPIL
     VMGILFGLAM DYEVFLVSRM REEYVHGKSA IDAIRDGFVA SGPVVVAAAV IMFSVFAFFV
     PEGAGPIKQI AFALAVGVAV DAFLVRMTLV PAVMALLGDK AWWLPKWLDK LLPTFDVEGE
     VLTQKLAMAN WPGTDDIVHA EGLAVDGIVN PIDLSVPAGA VVGIVGPLGP RTGAAMALTG
     RLETTSGRAR VVGELLPESA STVRRRTTHL DLALVRDTVQ ALRSIIPRTG EAIVVDSVDA
     VGSAAERDAL AQLVSLARTE RSFALFLCAT SAAHLEDFHP DGVMTVAETH LQESAV
//