ID A0A3M0IIF5_HIRRU Unreviewed; 885 AA.
AC A0A3M0IIF5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};
GN ORFNames=DUI87_35484 {ECO:0000313|EMBL:RMB88148.1};
OS Hirundo rustica rustica.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC Hirundo.
OX NCBI_TaxID=333673 {ECO:0000313|EMBL:RMB88148.1, ECO:0000313|Proteomes:UP000269221};
RN [1] {ECO:0000313|EMBL:RMB88148.1, ECO:0000313|Proteomes:UP000269221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chelidonia {ECO:0000313|EMBL:RMB88148.1};
RC TISSUE=Blood {ECO:0000313|EMBL:RMB88148.1};
RA Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT "A high quality draft genome assembly of the barn swallow (H. rustica
RT rustica).";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283,
CC ECO:0000256|RuleBase:RU000394}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMB88148.1}.
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DR EMBL; QRBI01000350; RMB88148.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M0IIF5; -.
DR STRING; 333673.A0A3M0IIF5; -.
DR Proteomes; UP000269221; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd01369; KISc_KHC_KIF5; 1.
DR Gene3D; 6.10.250.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47968; CENTROMERE PROTEIN E; 1.
DR PANTHER; PTHR47968:SF56; KINESIN MOTOR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|RuleBase:RU000394};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000269221}.
FT DOMAIN 1..293
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 336..377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 815..834
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 381..482
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 565..648
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 675..809
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 655..669
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 54..61
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 885 AA; 99325 MW; 9E2F688FB6B55899 CRC64;
MAEPSSECSI KGKPYVFDRV FPPNTTQEQV YHACAMQIVK DVLAGYNGTI FAYGQTSSGK
THTMELHDPQ QMGIIPRIAR DIFNHIYSMD ENLEFHIKVS YFEIYLDKIR DLLDMTKTNL
SVHEDKNRVP YVKGCTERFV SSPEEILDVI DEGKSNRHVA VTNMNEHSSR SHSIFLIHIK
QENVETEQKL SGKLYLVDLA GSEKVSKTGA EGAVLDEAKN INKSLSALGN VISALAEGTK
AYVPYRDSKM TRILQDSLGG NCRTTMFICC SPSSYNDAET KSTLMFGQRA KTIKNTASVN
LELTAEQWKK KFEKEKEKNK ALRETLARLE AELSRWRSGE AVPETEQLNE AEPGPGEGPG
EGQGGVPEEP PLNDNSSSIV IHISDEERRK YEEEIRKLYK QLDDKDDEIN QQSQIMEKLK
QQMLDQEEVL AAARGGGEAA RRELAALRAE HGAARAEVTE VLAALEELAR SYDRKAQEAE
DTGRHNRRLA DELARTEATT LSLESELSRA RELGGQQRRR AAEVLNGLLR DLSELSALVG
SGDIKLPVEV SGAIEEEFAV ARLYISKIKS EVKSVVKRCR QLENLQVECH RKLEVTGREL
SSCQLLISQH EAKIRSLTEY AQSLELRKRH LEEAHDALGE ELARLQAQEA AQGAARKQRE
QDESQDTDEV KAALELQLES QREAQHKQLA RLRDEVNERQ KTIDELRELL YERHEQSKQD
LKGLEETVAR ELQTLHNLRK LFVQDVTTRV KKLVRDNADL RCELPKLEKR LRATAGRVQA
LEGALRAAKE GARLDKRRYQ QEVERIREAV RARGARRGPG AHIAKPVRPG QVPSPTGLSY
TNSLFQGYPG GSPLPGPHGL SDLSCACEAE EAARLLPLRQ ETAAS
//
