ID   A0A3M0IS77_HIRRU        Unreviewed;      1275 AA.
AC   A0A3M0IS77;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN   ORFNames=DUI87_31957 {ECO:0000313|EMBL:RMB91727.1};
OS   Hirundo rustica rustica.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC   Hirundo.
OX   NCBI_TaxID=333673 {ECO:0000313|EMBL:RMB91727.1, ECO:0000313|Proteomes:UP000269221};
RN   [1] {ECO:0000313|EMBL:RMB91727.1, ECO:0000313|Proteomes:UP000269221}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Chelidonia {ECO:0000313|EMBL:RMB91727.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:RMB91727.1};
RA   Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA   Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT   "A high quality draft genome assembly of the barn swallow (H. rustica
RT   rustica).";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMB91727.1}.
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DR   EMBL; QRBI01000235; RMB91727.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M0IS77; -.
DR   STRING; 333673.A0A3M0IS77; -.
DR   Proteomes; UP000269221; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR042480; DISP3.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR46687; PROTEIN DISPATCHED HOMOLOG 3; 1.
DR   PANTHER; PTHR46687:SF1; PROTEIN DISPATCHED HOMOLOG 3; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000269221};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        452..469
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        475..498
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        505..527
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        547..567
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        579..608
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1066..1084
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1090..1111
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1172..1198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1204..1227
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1239..1261
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          499..604
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   REGION          216..237
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        219..237
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1275 AA;  140737 MW;  020DEE99D4757261 CRC64;
     MLCTCSSCFQ ITDIQVCAGR EEKRAERRDI PAVSAQLWWP KSVLDMDTED DPLLQDAWLE
     EEDEEVAFSS RKRREGALLC GKSPCRVRPL CVTLPVSGFW NIVGWVFTNP YCAGFILFLG
     CAIPAVLAVV MFLHYPALDI DISYNAFEIR NHESSQRFDA LALALKSQFG SWGRNRRDLA
     DFTSETLQRL IFEQLQQLHL NASHLGVSAR VKRSPAEART GSLQPQAQLS AGNQTSRIGR
     GAPRWDYSST YISANTQAHA HWRIELIFLA RGDSENNIFT TERLVTIHEV ERKIMDHPRF
     REFCWKPHEV LKDLPLGSYS YCSPPSSLMT YFFPTERGGK IYYDGMGQDL ADIQGSLELA
     MTHPEFYWYV DEGLSAENKK SSLLRSEILF GAPLPNYYSV EDRWEEQRHK FQNFVITYVA
     MLAKQSTSKV QVLYGGTDLF DYEVRRTFNN DMLLAFISSS CIAVLVYLLT SCSVFLSFFG
     IASIGLSCLV ALFLYHVVFG IQYLGILNGV AAFVIVGIGV DDVFVFVNTY RQATHLKDLR
     LRMIHTIQTA GKATFFTSLT TAAAYAANIF SQIPAVHDFG LFMSLIVSCC WVAVLFTMPA
     ALGIWTLYVS PLESSCQASC SQKCTKKSAL HLAEDLFIAS DTTSRAGQET LPYLDDDIPL
     LSVEEEPVSL EMGDVPLVSV MPENLQLSAE KSSRGHLITH LQELLEHWVL WSAVKSRWVI
     VASRAPVLFR PDTNIQVLLD LKYNLSAEGI SCITCSELQG TVYISKSRSK GRPAIYRFSL
     NASVPAPWQM VSPGDGEVPS FQVYRVPFGN FTRKLTACVS TVGLLKQMSP RKWMMTTLSC
     DTKKGWKFDF SFYVASKEQQ RTRKLYFAQS HKPPYHGRVC VAPPGCLLSS SPDGPTKGIL
     YVPSEKAPRA KLSATSGFNP CMNTGCGKPA VRPLVDTGAM VFVVFGIRGV NRTRRPDNHV
     LGDMGSVIYD DSFDLFKEIG NLCRLCKAIA SNSELVKPGG AQCLPSGYSI SSFLQMLHPE
     CKNIPEPNLL PGQLSHGAVG VKDGKVQWIS MAFESAKPKE IGVQSALYGL VLSLLICVAA
     VAVFTTHILL LLPVLLSILG VVCLVVTIMY WSGWEMGAVE AISLSILVGS SVDYCVHLVE
     GYLLAGENLP LHQAEDPTAC RQWRTMEAVR HVGVAIVSSA VTTVIATVPL FFCIIAPFAK
     FGKIVALNTG VSILYTLTVS TALLSIMGPG TFTRSRTSCL KAVLGVLLAG LLGLCICLAL
     LKSGFKLPLS NGTAL
//