ID A0A3M0J2I1_HIRRU Unreviewed; 380 AA.
AC A0A3M0J2I1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=Peptidase A2 domain-containing protein {ECO:0000259|PROSITE:PS50175};
GN ORFNames=DUI87_30412 {ECO:0000313|EMBL:RMB93183.1};
OS Hirundo rustica rustica.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC Hirundo.
OX NCBI_TaxID=333673 {ECO:0000313|EMBL:RMB93183.1, ECO:0000313|Proteomes:UP000269221};
RN [1] {ECO:0000313|EMBL:RMB93183.1, ECO:0000313|Proteomes:UP000269221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chelidonia {ECO:0000313|EMBL:RMB93183.1};
RC TISSUE=Blood {ECO:0000313|EMBL:RMB93183.1};
RA Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT "A high quality draft genome assembly of the barn swallow (H. rustica
RT rustica).";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMB93183.1}.
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DR EMBL; QRBI01000211; RMB93183.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M0J2I1; -.
DR STRING; 333673.A0A3M0J2I1; -.
DR Proteomes; UP000269221; Unassembled WGS sequence.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd05482; HIV_retropepsin_like; 1.
DR CDD; cd07557; trimeric_dUTPase; 1.
DR Gene3D; 1.10.1200.30; -; 1.
DR Gene3D; 2.70.40.10; -; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR029054; dUTPase-like.
DR InterPro; IPR036157; dUTPase-like_sf.
DR InterPro; IPR033704; dUTPase_trimeric.
DR InterPro; IPR045345; Gag_p24_C.
DR InterPro; IPR001995; Peptidase_A2_cat.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR034170; Retropepsin-like_cat_dom.
DR InterPro; IPR018061; Retropepsins.
DR InterPro; IPR008916; Retrov_capsid_C.
DR PANTHER; PTHR19422; GAG RETROVIRAL POLYPROTEIN; 1.
DR PANTHER; PTHR19422:SF123; HUMAN ENDOGENOUS RETROVIRUS K ENDOPEPTIDASE; 1.
DR Pfam; PF00692; dUTPase; 1.
DR Pfam; PF19317; Gag_p24_C; 1.
DR Pfam; PF00077; RVP; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF51283; dUTPase-like; 1.
DR SUPFAM; SSF47353; Retrovirus capsid dimerization domain-like; 1.
DR PROSITE; PS50175; ASP_PROT_RETROV; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000269221};
KW Ribosomal frameshifting {ECO:0000256|ARBA:ARBA00022758};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT DOMAIN 293..368
FT /note="Peptidase A2"
FT /evidence="ECO:0000259|PROSITE:PS50175"
SQ SEQUENCE 380 AA; 39823 MW; FBB1B2FC9191A8F5 CRC64;
MAALVQTLQL ATPQQPFATI VQGVDEPFLC FAGRLTAAVE KQVSDPAARK LMIQSVAQGN
CNAACKRIIE ALPGEPSMSD MVGACAKISP SSQQVVAVHT AVQPAVATIV QPTVATAVQP
AVPAAVQPAV AAAVQPDWVV PQGVQQQQWG ARARKKQSTE SVVIDSDKIH KVPLDAFGPL
GDGMSAFLMG RSSATIQGII VHLGLIDADF SGQIHAMVST PTSPLTIPKG TRIAQLVPFK
SSVSRTEDRS RGDGGFGSTG PPQVCWTAVL TKDRPETLCT VSMVGATPSE IHLRGLLDTG
ADVSILSLAA WPPQCPLTLA KTSISGLGGT KQCYVSRNPV AITNPEGQTA IIWPHVTEIP
QNLWGRDVLA AWGVRLGTDF
//
