ID A0A3M0JP29_HIRRU Unreviewed; 1733 AA.
AC A0A3M0JP29;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Rap-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DUI87_23101 {ECO:0000313|EMBL:RMC00490.1};
OS Hirundo rustica rustica.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC Hirundo.
OX NCBI_TaxID=333673 {ECO:0000313|EMBL:RMC00490.1, ECO:0000313|Proteomes:UP000269221};
RN [1] {ECO:0000313|EMBL:RMC00490.1, ECO:0000313|Proteomes:UP000269221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chelidonia {ECO:0000313|EMBL:RMC00490.1};
RC TISSUE=Blood {ECO:0000313|EMBL:RMC00490.1};
RA Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT "A high quality draft genome assembly of the barn swallow (H. rustica
RT rustica).";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMC00490.1}.
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DR EMBL; QRBI01000144; RMC00490.1; -; Genomic_DNA.
DR STRING; 333673.A0A3M0JP29; -.
DR Proteomes; UP000269221; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 6.10.140.210; -; 1.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR InterPro; IPR021818; SIPA1L_C.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR15711:SF10; SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 1; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR Pfam; PF11881; SPAR_C; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000269221}.
FT DOMAIN 561..778
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT DOMAIN 916..980
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 44..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 218..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1030..1092
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1109..1163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1200..1241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1260..1292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1311..1341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1355..1406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1479..1506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1575..1594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1670..1718
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1030..1058
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1202..1232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1260..1282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1325..1341
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1481..1506
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1733 AA; 192024 MW; E4C93C78822EE6B9 CRC64;
MTSLKRSQTE RAVATGVSVG TDGTSKVHSD DFYMRRFRSQ NGSLGSAVMA PVGPPRNESS
HHVTSTPGVP KMGSIQSTLK NKTRQSENLD SRFLTPDGYP SSPRKALRRI RQRSNSDITI
SELDVDSFDE CISPTFKSGP SLHREYGSTS SIDKQGTSGE SFFDLLKGYK DEKSDQRSPG
STKLGELLIA SGSKGSGFSL DVIDGPITQR ENLRLFKERE KPLKRRSKSE TGDSSIFRKL
RNAKGEGELG KSSDLEDNRS EDSIKPWTCP KCFAHYDVQS ILFDLNEAAI NRHNVIKRRN
TTTGASAAAV ASLVSGPLSH SASFNSPMGS TEDLNSKGSL NMDQGDDKSN ELVMSCPYFR
NEIGGEGERK ISLSKSNSGS FSGCESASFE STLSSHCTNA GVAVLEVPKE NLILHLDRVK
RYIVEHVDLG AYYYRKFFYQ KVLVRDIIFP CSQRSAKAIW PEHWNYFGAD ENLGPVAVSI
RREKPEEIKE NGPQYNYRII FRTSELMTLR GSVLEDAIPS TAKHCTARGL PLKEVLEYVV
PELNIHCLRL AFNTPKVTEQ LMKLDEQGLS YQLKVGIMYC KAGQSTEEEM YNNESAGPAF
EEFLQLLGER VRLKGFDKYR AQLDTKTDST GTHSLYTTYK DYEIMFHVST MLPYTPNNKQ
QLLRKRHIGN DIVTIVFQEP GAQPFSPKNI RSHFQHVFVI VRVHGPCTDS VCYSVAVTRS
RDVPSFGPPI PKGVTFPKSN VFRDFLLAKV INAENAAHKS EKFRAMATRT RQEYLKDLAE
KNVTNTPIDP SGKFPFISLA SKKKEKSKPY PGAEIYSSGA IVWSVHAKDY SKGVEIDCLL
GISNEFVVLI EQDTKSVVFN CSCRDVIGWT STDTNIKIFY ERGECVSLES FISNIDDIKE
IVKRLELVTK GCETVEMTLR RNGLGQLGFH VNYEGIVADV EPYGYAWQAG LRQGSRLVEI
CKVAVATLSH EQMIDLLRTS VTVKVVIVPP YEDCTPRRSS SENYRMPVME YKVNEGMPYE
FKFPFRNNNK WQRNASKGQG PHVAQVPSQI QSPVPSRITS GKGEGKMPPP ERANIPRSIS
SDGRPLESRR LSPGSDVYVT VSSIALARSQ QCRNSPSNLS SSSDTGSTGG TYRQKSMPEG
QNTQSDTGGS GKSTPSWQRS EDSIADQMEP TCHLPAVSKV LPSFRESPSG RLMRQDPVVH
LSPNKQGHSD SHYSSHSSSN TLSSNASSAH SDEKWYDSGE RTESELNSYN YLQGTSADSG
IDTTSYGPSH GSTASLGAAT SPRTGLTKEK VAPLWHSSSE VVSIADRTLE KDSHMDRKAE
SSLSLDIHSK SQPASNPLTR ENSAYSLSDA VSHTSTMSSR HSASPVVFTS ARSSPKEELH
SATSPQLAPS FSSSSSSSSG PRTFYPRQGA TSKYLIGWKK PEGTINSVGF MDSRKRHQSD
GNEMAHPRLR ASARDLRASP KRASKSTVEE ELKKLIDLDS PTPESQKNFK SHTLSCQSPF
PSTPTTRRAL QRTLSDESIY SGQRDHFFTS RASLLDQAMP NDVLFTSTYP SLPKSLPLRR
PSYTLGMKSL HGEFSASDSS LTDIQEQRRQ PMPDPGLMPL PDSASDLDWS NLVDAAKAFE
VQRASFFAAA DENHRPVSAA SSSDQAEDQL TAQIKPYTGK ESPPTLASKV DQLEGLLKML
QEDLRKEKED KASLQAEVQH LREDNLRLQE ESQNATEKLK KFTEWVFNTI DMN
//
