ID   A0A3M0JP87_HIRRU        Unreviewed;      1036 AA.
AC   A0A3M0JP87;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=VWFD domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DUI87_21263 {ECO:0000313|EMBL:RMC02101.1};
OS   Hirundo rustica rustica.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC   Hirundo.
OX   NCBI_TaxID=333673 {ECO:0000313|EMBL:RMC02101.1, ECO:0000313|Proteomes:UP000269221};
RN   [1] {ECO:0000313|EMBL:RMC02101.1, ECO:0000313|Proteomes:UP000269221}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Chelidonia {ECO:0000313|EMBL:RMC02101.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:RMC02101.1};
RA   Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA   Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT   "A high quality draft genome assembly of the barn swallow (H. rustica
RT   rustica).";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMC02101.1}.
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DR   EMBL; QRBI01000134; RMC02101.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M0JP87; -.
DR   STRING; 333673.A0A3M0JP87; -.
DR   Proteomes; UP000269221; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   CDD; cd06263; MAM; 1.
DR   CDD; cd19941; TIL; 1.
DR   Gene3D; 2.60.120.200; -; 1.
DR   Gene3D; 2.10.25.10; Laminin; 1.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR000998; MAM_dom.
DR   InterPro; IPR036084; Ser_inhib-like_sf.
DR   InterPro; IPR002919; TIL_dom.
DR   InterPro; IPR025615; TILa_dom.
DR   InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR   InterPro; IPR001846; VWF_type-D.
DR   PANTHER; PTHR46160; ALPHA-TECTORIN-RELATED; 1.
DR   PANTHER; PTHR46160:SF5; PROTEIN CBG11501; 1.
DR   Pfam; PF08742; C8; 2.
DR   Pfam; PF00629; MAM; 1.
DR   Pfam; PF01826; TIL; 1.
DR   Pfam; PF12714; TILa; 1.
DR   Pfam; PF00094; VWD; 3.
DR   SMART; SM00832; C8; 2.
DR   SMART; SM00137; MAM; 1.
DR   SMART; SM00216; VWD; 3.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF57567; Serine protease inhibitors; 1.
DR   PROSITE; PS50060; MAM_2; 1.
DR   PROSITE; PS51233; VWFD; 3.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Reference proteome {ECO:0000313|Proteomes:UP000269221}.
FT   DOMAIN          23..186
FT                   /note="MAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50060"
FT   DOMAIN          208..385
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   DOMAIN          633..816
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   DOMAIN          880..1036
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
SQ   SEQUENCE   1036 AA;  115048 MW;  CFEB548F41E10645 CRC64;
     MFKIKQRPRG GLRTWDPETA YLTRCDFNNN SRPFCDWTQP CNVNQGVWIR TKHDTPTDGT
     GPDGDYPDGK GYFIYQEASN LIPFDTNRLE SPDTVVSGKI CIDFWYYMFG SEEMNELRVL
     VQDGTGESVV WHRKGNQSSL WKYGAITHTF PTQRKIKVIF EAVRGLTEYG DTALDNVRVR
     DGPCEAVPTP VPTIPTPTEP TPLPVTEAIC SIQGDPHYNT FDKQRHDFMG TCTYTLSKLC
     ESNSSLPYFN VEAANEHRGG NTRVSYVQYV DIDVYGYRIN LGQKRAVKVN GDSQVVPVTL
     VPGVNISLSG QYVVVTTDFG LQVKFDGNHR AEITLPSTYM SKVCGICGNY NGQKADDFLN
     PDGEMEANST SLGNSWQVYN DSRCSPDDGH TPVCTDDEKH MIQSNAYCGL ITDPNGPFQN
     CHAVVDPLSY FEDCQYDLCE LHLNDAALCE SLQAYADVCQ AAGVQLKPWR NATFCRCGGK
     HQSVPYRHSH SRFQMGEEPT RIRSLDLKTR TEAKTLACPA NSHYEPCGAA CPATCVDPMA
     PVTCSLPCVE GCVCDSGYLL YNDRCVPSQQ CGCWHNGQHY PVGSEFWTDN TCSSKCTCPA
     RGSKVQCFNA SCPAGQYCGV QNGTPVCLEH SYGICHVHGD PHYQTFDKVT HNFMGNCTYT
     LAKVCSNTTS LPYFNMEAKN EHRGSSRVSY VREVVVEVYG QRIVILKQQK SHVLVNSLRQ
     TLPVSAAGGA ITVGKSGRYI VLETDFKLRV SYDADHSVEV KVPTTYFNLT CGIAVQKKRN
     LYRSDQFCGI LTTTRPSSFE RCHGVINPQD YFDTCLYDLC ALKWWPGVSC VLPLEAYADA
     CQAAVVTLLS LEECYLLPYY DPCMTGVLPP VLIDKRHRTA PSLVWRAVHE GESSVDENCT
     RRCRCEANGQ MVCSALSCGE DEVCKIRGCQ RGCYPASTAI CHIYGDPHYS TFDGKLHHFQ
     GSCNYTVVNG VEEILPCSPS SGVQVLSSGF YTMVMTDFGL RVKFDGKHRV EVTLPSTFGQ
     QKVCGMCGNY NGDSSR
//