ID   A0A3M0JQD3_HIRRU        Unreviewed;       490 AA.
AC   A0A3M0JQD3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=HSF-type DNA-binding domain-containing protein {ECO:0000259|SMART:SM00415};
GN   ORFNames=DUI87_20885 {ECO:0000313|EMBL:RMC02491.1};
OS   Hirundo rustica rustica.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC   Hirundo.
OX   NCBI_TaxID=333673 {ECO:0000313|EMBL:RMC02491.1, ECO:0000313|Proteomes:UP000269221};
RN   [1] {ECO:0000313|EMBL:RMC02491.1, ECO:0000313|Proteomes:UP000269221}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Chelidonia {ECO:0000313|EMBL:RMC02491.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:RMC02491.1};
RA   Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA   Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT   "A high quality draft genome assembly of the barn swallow (H. rustica
RT   rustica).";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|ARBA:ARBA00006403,
CC       ECO:0000256|RuleBase:RU004020}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMC02491.1}.
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DR   EMBL; QRBI01000133; RMC02491.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M0JQD3; -.
DR   STRING; 333673.A0A3M0JQD3; -.
DR   Proteomes; UP000269221; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR000232; HSF_DNA-bd.
DR   InterPro; IPR027725; HSF_fam.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10015:SF278; HEAT SHOCK FACTOR PROTEIN 5; 1.
DR   PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR   Pfam; PF00447; HSF_DNA-bind; 1.
DR   SMART; SM00415; HSF; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000269221}.
FT   DOMAIN          14..125
FT                   /note="HSF-type DNA-binding"
FT                   /evidence="ECO:0000259|SMART:SM00415"
FT   REGION          118..177
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          272..321
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          340..414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        301..316
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   490 AA;  53975 MW;  972BE96A604F2976 CRC64;
     MDAMAQLPLP AGLGAGTFHA KLWSLVNDPR ICSLRWDSEA RGLLVDRSLF ERELLRPGGA
     QGPAPHAFRA TQFSSFVRQL YRYGFRKVPG RAGAAAPGDA GAWVHYSNPW FRRDRPDLCS
     ASGAGARPTR SGGRRGRRGT GPANRGSKQL PGPRPLPDER NGRARFQPLP RERQPLARCP
     PCSFHLLHRE RPGPARREGA EPLQELYGER PLPAERELLR VPPCHFQGFH GEQLLPPRWE
     GPRSRMQELY GEQPPPLDRE LLWMQPCSFQ QLHREQQPPA SNPPAAAGTS APHAPAGSAG
     CAASTASSSA QNAPAQEESP ALDLGQAIEK MIREIRNSLP VKAPSAQGNI NVAPESPGED
     PMNRAEAEEA SSDTESCRNS SPEPEEPGLH RVQVVSSCDP SNGESMDPTV KKPDGSYRLV
     QDLREVNKRT QPRYPVVPNP YTLLSKVPPQ HQWFSVVDLK DASWACPLAK ESRDIFAFEW
     EDPKLEESSN
//