ID A0A3M0K0E4_HIRRU Unreviewed; 1391 AA.
AC A0A3M0K0E4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=peptidylprolyl isomerase {ECO:0000256|ARBA:ARBA00013194};
DE EC=5.2.1.8 {ECO:0000256|ARBA:ARBA00013194};
GN ORFNames=DUI87_17839 {ECO:0000313|EMBL:RMC04670.1};
OS Hirundo rustica rustica.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC Hirundo.
OX NCBI_TaxID=333673 {ECO:0000313|EMBL:RMC04670.1, ECO:0000313|Proteomes:UP000269221};
RN [1] {ECO:0000313|EMBL:RMC04670.1, ECO:0000313|Proteomes:UP000269221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chelidonia {ECO:0000313|EMBL:RMC04670.1};
RC TISSUE=Blood {ECO:0000313|EMBL:RMC04670.1};
RA Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT "A high quality draft genome assembly of the barn swallow (H. rustica
RT rustica).";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC ChEBI:CHEBI:83834; EC=5.2.1.8;
CC Evidence={ECO:0000256|ARBA:ARBA00000971};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMC04670.1}.
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DR EMBL; QRBI01000123; RMC04670.1; -; Genomic_DNA.
DR STRING; 333673.A0A3M0K0E4; -.
DR Proteomes; UP000269221; Unassembled WGS sequence.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR Gene3D; 2.40.100.10; Cyclophilin-like; 2.
DR InterPro; IPR029000; Cyclophilin-like_dom_sf.
DR InterPro; IPR020892; Cyclophilin-type_PPIase_CS.
DR InterPro; IPR002130; Cyclophilin-type_PPIase_dom.
DR PANTHER; PTHR11071; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; 1.
DR PANTHER; PTHR11071:SF561; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE H; 1.
DR Pfam; PF00160; Pro_isomerase; 2.
DR SUPFAM; SSF50891; Cyclophilin-like; 1.
DR PROSITE; PS00170; CSA_PPIASE_1; 1.
DR PROSITE; PS50072; CSA_PPIASE_2; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000269221};
KW Rotamase {ECO:0000256|ARBA:ARBA00023110}.
FT DOMAIN 10..120
FT /note="PPIase cyclophilin-type"
FT /evidence="ECO:0000259|PROSITE:PS50072"
FT REGION 132..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 600..992
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1007..1048
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1199..1391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..157
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..184
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..341
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..392
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..441
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..456
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..485
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..515
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..562
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..636
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 637..686
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..714
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 723..737
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 738..752
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..854
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 879..910
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 913..952
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 974..992
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1018..1048
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1214..1272
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1273..1287
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1288..1343
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1344..1371
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1372..1391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1391 AA; 157499 MW; 0476C965652AB8CE CRC64;
MGVQDRPQCF FEIEINREPG EKGIGKTTGK KLCYKGTTFH RVVKNFMIQG GDFSEGNGKG
GESIYGGYFK ENVVFCKMKS VHVVFGLVIS GFEVIEQIEN LKTDTASRPY ADVRVIDCGV
LVTRSAKDAL EKRKKVCSDS EASESSSSAS SSSESSSESE AENDRSRRRK RKRRTKTKQS
RKRRKEERKK EDPSSLSDKS DVADKVDLSA KRDKPVVRPE EIPPVPENRF LLRRDVPVVN
VEPEPKLLDA APVLTDQKPS VSKSGRKIKG RGTIRYHTPP RSRSCSESDD EESSETPPHW
KEEMQRLRTY RAPSGEKWSK GDKLSDPCTS RWDERSASRR SRSWSHNGYA DLSAVRYSSH
HKKHRKEKKK VKHKKKSKKQ KHFKRHKQTK KKKTSASSDV ESSHSFHRRT KSSCDRERKS
RSSSLSSRRS SRRDWSKSDK EDQSLSSLSS RGSRSYYRSR SRSRSKSRSY SRRSSRSRSA
SKSSRSRSRS RSSSNPRQQK TVPNSPRNIS ARLNDTKLTK AAEPVRAVIL PSDKVIVPPV
VPENLPVIPL SDSPPPSRWK PGQKPWKPSY ERIQEMKAKT THLIPTQTNY NLVVVKEANA
TSSSYRKQER SSESDRSGYS KGRSDRSSES WQRSRSRSSR SRSYSRSYSR SRSPSSSRTK
SPSSGRSPSP SKYRSDRSGY SESTSDYSLS DEDRHRNKRK SASSDPKARG LKLRQETSSE
STLPYKHPKD YDESSQGLKE SDSFSSSDFS SDSERSAKAK VVQEKEGRFP LEGDAEKQGK
NNLSSERREE KAKGERDSDH SKKKAAKEKC SEQPRGGAKT KRKSYSGSKW DSESNSERGD
AKHNRGDSRP SSGKEEGEAT SGSDTELSVT KRIKKRSNSS EGFLGSDCTW KTSKQLSSSE
SESSCSSSAD ARGKSKKHKH GLKKTPKKSH SKKAKEKSKG KKEKKHKVQK RKEMFHWQPP
LEFGEEEDDE ISEKPVTKDD KKEKQLSRDI KDKKQVYEKD EIVTDKVGNG EKPCVNENLL
DKNTTCGASP DRSNLNKEPI ETSTSTGILN SGINVASCKS EIKQAEENNQ NGLEDVIQRD
DYMEICTPDR NSPGKVDVDV LSPVILAAKP LSADVKEELQ VETPEQDAVK LGNNIRDFIN
IEEETGRQEN NSAPVSGAKD CSLKSEICEN IQSNMIDNKW KPLQGVGNLK PTTISTTTEV
KNVASAPEPK PAGLRIEIKA KNKVRPGSLF DEVRKTARLN RRPRNQESSS EEESPSRDDN
SPSRSLSRSR SKSESKSRHR TRSISYSHSR SRSRSSTYSY RSRSYSRSWS RGWYSSDRSR
SRSSSYHSYK SRSRSYTYDS YYSRSRSRSK RSDSYRRSRS YDRRSRSYGS DSDSDRSYSN
NRSPSESSRY S
//
