ID A0A3M0K4F1_HIRRU Unreviewed; 948 AA.
AC A0A3M0K4F1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Protein ECT2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=DUI87_21129 {ECO:0000313|EMBL:RMC01967.1};
OS Hirundo rustica rustica.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC Hirundo.
OX NCBI_TaxID=333673 {ECO:0000313|EMBL:RMC01967.1, ECO:0000313|Proteomes:UP000269221};
RN [1] {ECO:0000313|EMBL:RMC01967.1, ECO:0000313|Proteomes:UP000269221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chelidonia {ECO:0000313|EMBL:RMC01967.1};
RC TISSUE=Blood {ECO:0000313|EMBL:RMC01967.1};
RA Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT "A high quality draft genome assembly of the barn swallow (H. rustica
RT rustica).";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMC01967.1}.
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DR EMBL; QRBI01000134; RMC01967.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M0K4F1; -.
DR STRING; 333673.A0A3M0K4F1; -.
DR Proteomes; UP000269221; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:2000431; P:regulation of cytokinesis, actomyosin contractile ring assembly; IEA:InterPro.
DR CDD; cd17733; BRCT_Ect2_rpt1; 1.
DR CDD; cd17732; BRCT_Ect2_rpt2; 1.
DR CDD; cd01229; PH_Ect2; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 3.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR026817; Ect2.
DR InterPro; IPR049396; ECT2_BRCT0.
DR InterPro; IPR049395; ECT2_PH.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR16777; PROTEIN ECT2; 1.
DR PANTHER; PTHR16777:SF2; PROTEIN ECT2; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF21243; ECT2_BRCT0; 1.
DR Pfam; PF21242; ECT2_PH; 1.
DR Pfam; PF12738; PTCB-BRCT; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00292; BRCT; 2.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF52113; BRCT domain; 2.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50172; BRCT; 2.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000269221}.
FT DOMAIN 182..258
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 270..358
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 462..605
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 393..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 874..894
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 417..453
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 948 AA; 106453 MW; 59F3B8982743E06C CRC64;
MCAVAALRQQ RTGTSMFRRN LVPSSRYGGK LDFLKKDFLR VQRKGAPVEK PVEVGLELQN
DGPSGYLKVT KVPQTIKIME VPVIKIKESS PDKSEEKLIK SIIHMEIKMP YIKTDTIEEL
GDSDSPEFET IFVVSDFQAP IFSNLCKADC RVIGPPVVLH CAHQGEPLPF SCRPLYCASM
LNLVLCFTGF RKKDELVKLV TLVHHMGGII RRDFSSKVTH LVANSTHGDK FRIAVSLGIP
IVKAEWIYKA WEKRNEIDFS AADDNFRNQF KVPPFQDCML SFLGFSDDEK ANMEEMTEMQ
GGHYLPVGDE RCTHLVVEES TVKDLPFEPL KKLYVVKQEW FWGSIQMDAR AGESMYLFEK
SESPDFKKSV SLLSLSTPNS NRKRRRLKET LAQLTRETDL SPFPPRKRPS AEHSLSIGSL
LDISNTPESS TANGETPKSC ARPSKNSTPL PLKQSARWQV AKELYQTESN YVDILTTIIQ
EDLEDLMMNW TESKSIGDII LKYSKDLLKT YPPFVNFFEM SKETITRCEK QKPRFHAFLK
INQAKPECGR QSLAELLIRP VQRLPSVALL LNDIKKHTAE ENPDKITLER AIESLKEVMT
HINEDKRKTE AQRQFFDVVY EVDGCPANLL SSHRSLVQRL ETVALGDDLC DRGEQVTLFL
FNDCLEIARK RHKVIGAFKS PHGHTRPPAS LKHVVLMPLS QIKKVLDIRE TEDCQKAFAL
VVRPPTELNN KLLSFQMTTE EPRKEDWLKT LCRHVANTIC KADAENLIYV ADPDSVEVST
KDMDSTLSRA SRAIKKTSKK VTRAFSFSKT PKRALRRALM SHSATEGRSP SSANEGYIGS
RLTSTSSLAI ARSSSTCSLS GAVKCAVNVH RSSSVDWSSQ NSKPRPVLCP GSPNTHLSNA
VETKASSNLE SLNHHALDRP CAFPVITCAD AGDDNQRGAG KFCASDPD
//
