ID A0A3M0K532_HIRRU Unreviewed; 763 AA.
AC A0A3M0K532;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=phosphopyruvate hydratase {ECO:0000256|ARBA:ARBA00012058};
DE EC=4.2.1.11 {ECO:0000256|ARBA:ARBA00012058};
DE AltName: Full=2-phospho-D-glycerate hydro-lyase {ECO:0000256|ARBA:ARBA00031125};
GN ORFNames=DUI87_17067 {ECO:0000313|EMBL:RMC07591.1};
OS Hirundo rustica rustica.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC Hirundo.
OX NCBI_TaxID=333673 {ECO:0000313|EMBL:RMC07591.1, ECO:0000313|Proteomes:UP000269221};
RN [1] {ECO:0000313|EMBL:RMC07591.1, ECO:0000313|Proteomes:UP000269221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chelidonia {ECO:0000313|EMBL:RMC07591.1};
RC TISSUE=Blood {ECO:0000313|EMBL:RMC07591.1};
RA Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT "A high quality draft genome assembly of the barn swallow (H. rustica
RT rustica).";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-
CC glyceraldehyde 3-phosphate: step 4/5. {ECO:0000256|ARBA:ARBA00005031}.
CC -!- SIMILARITY: Belongs to the enolase family.
CC {ECO:0000256|ARBA:ARBA00009604}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMC07591.1}.
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DR EMBL; QRBI01000120; RMC07591.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M0K532; -.
DR STRING; 333673.A0A3M0K532; -.
DR UniPathway; UPA00109; UER00187.
DR Proteomes; UP000269221; Unassembled WGS sequence.
DR GO; GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0004634; F:phosphopyruvate hydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR CDD; cd03313; enolase; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR HAMAP; MF_00318; Enolase; 1.
DR InterPro; IPR000941; Enolase.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR020810; Enolase_C.
DR InterPro; IPR020809; Enolase_CS.
DR InterPro; IPR020811; Enolase_N.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR NCBIfam; TIGR01060; eno; 1.
DR PANTHER; PTHR11902; ENOLASE; 1.
DR PANTHER; PTHR11902:SF10; GAMMA-ENOLASE; 1.
DR Pfam; PF00113; Enolase_C; 1.
DR Pfam; PF03952; Enolase_N; 1.
DR Pfam; PF14580; LRR_9; 1.
DR PRINTS; PR00148; ENOLASE.
DR SFLD; SFLDF00002; enolase; 1.
DR SFLD; SFLDG00178; enolase; 1.
DR SMART; SM01192; Enolase_C; 1.
DR SMART; SM01193; Enolase_N; 1.
DR SMART; SM00365; LRR_SD22; 5.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS00164; ENOLASE; 1.
DR PROSITE; PS51450; LRR; 3.
PE 3: Inferred from homology;
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000269221}.
FT DOMAIN 332..463
FT /note="Enolase N-terminal"
FT /evidence="ECO:0000259|SMART:SM01193"
FT DOMAIN 471..760
FT /note="Enolase C-terminal TIM barrel"
FT /evidence="ECO:0000259|SMART:SM01192"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 292..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 763 AA; 84945 MW; EAB3F410EC87401C CRC64;
MQDEEPEEEK EEREEDEEKE EGDDEEKEGK EPAPCPLTEE ILKEGLSLLS KTGNGLAHAY
VKFEAKDKGL TDISLLERFI HLRYVDLSKN KLKDLAPLSS LTQLLWLKVD GNLLTSASMQ
EMPYLQVISF DRNQIVDLEG ITHPLLANLS LKENKIQTVL GLSQDQLFSL QVLELRGNQI
KTTAGLGVPK LKQLYLAKNT ICSLEGLEEF EQLETLHLRD NKLEALDGFC DSMKCLQYLN
LRNNGIKSFQ EVEKLQVLPM LQALVLMDNP CAEEPNYRLE VLSRLSQLQR LDKESVEEEE
REEAEKMRQT RKEKHFLNLS STPALGRLTM AVERIHAREI LDSRGNPTVE VDLYTHKGMF
RAAVPSGAST GIYEALELRD NDKSRFLGKG VLQAVDHINS TVAPALVGSG LSVVDQEKID
NLMLEMDGTE NKSKFGANAI LGVSLAVCKA GAAEKDVPLY RHIADLAGNS DLILPVPAFN
VINGGSHAGN KLAMQEFMIL PVGAESFRDA MRIGAEVYHN LKSVIKEKYG KDATNVGDEG
GFAPNILENS EALELLKEAI DKAGYTDKIV IGMDVAASEF YRDGKYDLDF KSPDDPSRYI
SGDELGDLYQ SFVRDYPVVS IEDPFDQDDW ENWSKFTANV GIQIVGDDLT VTNPKRIERA
VEEKACNCLL LKVNQIGSVT EAIQACKLAQ ENGWGVMVSH RSGETEDTFI ADLVVGLCTG
QIKTGAPCRS ERLAKYNQLM RIEEELGDEA RFAGHNFRNP SVL
//
