ID   A0A3M0K6V7_HIRRU        Unreviewed;       877 AA.
AC   A0A3M0K6V7;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN   ORFNames=DUI87_13896 {ECO:0000313|EMBL:RMC08902.1};
OS   Hirundo rustica rustica.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC   Hirundo.
OX   NCBI_TaxID=333673 {ECO:0000313|EMBL:RMC08902.1, ECO:0000313|Proteomes:UP000269221};
RN   [1] {ECO:0000313|EMBL:RMC08902.1, ECO:0000313|Proteomes:UP000269221}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Chelidonia {ECO:0000313|EMBL:RMC08902.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:RMC08902.1};
RA   Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA   Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT   "A high quality draft genome assembly of the barn swallow (H. rustica
RT   rustica).";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMC08902.1}.
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DR   EMBL; QRBI01000116; RMC08902.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M0K6V7; -.
DR   STRING; 333673.A0A3M0K6V7; -.
DR   Proteomes; UP000269221; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd01650; RT_nLTR_like; 1.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR33395:SF21; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR33395; TRANSCRIPTASE, PUTATIVE-RELATED-RELATED; 1.
DR   Pfam; PF03372; Exo_endo_phos; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000269221}.
FT   DOMAIN          448..703
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
SQ   SEQUENCE   877 AA;  100259 MW;  547BE08901E1BB43 CRC64;
     MVHQRNYDIV AITEMWWDDS HSWSTALDGY KLFRRDRKGR RGGGVALYIR GVLDVTGIET
     NDDEVESLWV KIKGKANKAD ILLGVCYRPP NQDEEVDNLF YKQLNNVSGS SALVLVGDFN
     LPDIFWELNT AEKQQSRKFL ECVEDNFLSQ LVSKPTRGGT MLDLLFTNRD GLVGDVEVGG
     RLGHSDHEII EFSIIGEKRR NINKISTLDF WRADFGLFKR LIQRVPWETV LENKRVQERW
     VCFKTEILRA QEQTVPVCRK MSRRSKRPVW MSNEVLKELR NKKKMYHLFK EGLISQEVFK
     GAARACRKKI REAKAQFELN LATSVKNNKK SFYKYINDKR KGITNLGSLL DEAGNLVTKD
     EEKAEMLNAF FASVFIGRTA YPQDNCPQGL VGGARDQNGP LVIQEEAVRE LLGHLDIYKS
     MGPDGIHPRV MRELADELAK PLSIIYQESW LTGEVPGDWK LANVTPVYKK GRKEDPGNYR
     PVSLTSVPGK IMEQFILSAI TQHLQDGQGI RPSQHGFTKG RSCLTNLVSF YDQVTRLVDA
     GRAVDVVYLD FSKAFDTVSH SILLDKLAAH GLDRSTLRWV RNWLDGRAQR VMVNGAASSW
     RPVTSGVPQG SVLGPVLFNI FIDDMDEGIE SFISKFADDT KLGECVDPLE GRRALQRDLD
     RLDEWAESNS MKFNKSKCRV LHFGHKNPLQ RYRLGTVWLD SVQAERDLGV LVDSRLDMSQ
     QCALVAKKAN GILACIRNCV TSRSREVILP LYSALVRPHL EYCVQFWAPQ FKKDVEMLER
     VQRRATRLVR GLEHKPYEER LKELGLFSLE KRRLRGDLIT LYNFLKGGCR QRHFQDTKEE
     QSISAAVVVE NSLVCWKAEH NWMLCPASTW FHSLSFC
//