ID   A0A3M0K859_HIRRU        Unreviewed;      1079 AA.
AC   A0A3M0K859;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   13-SEP-2023, entry version 13.
DE   RecName: Full=KLOT protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DUI87_16686 {ECO:0000313|EMBL:RMC07230.1};
OS   Hirundo rustica rustica.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC   Hirundo.
OX   NCBI_TaxID=333673 {ECO:0000313|EMBL:RMC07230.1, ECO:0000313|Proteomes:UP000269221};
RN   [1] {ECO:0000313|EMBL:RMC07230.1, ECO:0000313|Proteomes:UP000269221}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Chelidonia {ECO:0000313|EMBL:RMC07230.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:RMC07230.1};
RA   Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA   Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT   "A high quality draft genome assembly of the barn swallow (H. rustica
RT   rustica).";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMC07230.1}.
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DR   EMBL; QRBI01000120; RMC07230.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M0K859; -.
DR   STRING; 333673.A0A3M0K859; -.
DR   Proteomes; UP000269221; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 3.
DR   InterPro; IPR001360; Glyco_hydro_1.
DR   InterPro; IPR033132; Glyco_hydro_1_N_CS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10353; GLYCOSYL HYDROLASE; 1.
DR   PANTHER; PTHR10353:SF10; KLOTHO; 1.
DR   Pfam; PF00232; Glyco_hydro_1; 4.
DR   PRINTS; PR00131; GLHYDRLASE1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 2.
DR   PROSITE; PS00653; GLYCOSYL_HYDROL_F1_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000269221};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..1079
FT                   /note="KLOT protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017971775"
FT   TRANSMEM        1049..1070
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1079 AA;  123657 MW;  25BF661C16A78564 CRC64;
     MALASLLPPP LLLLLLLVGR PGLGAPGQGA GTWSRFARLP YPQDQLFLHD TFPDGFLWGA
     GSAAYQTEGG WRQGGKGASV WDTFAHRPAT PPGAAPPGPV GGDVASDSYN NVFRDVEGLR
     RLGVSHYRFS LSWARLLPNG TAPPNPAGLE HYGRLLARLR ELGVEPVVTL YHWDLPQALQ
     DAFGGWASPV LPRLFRDYAE LCFRHFGGQV RYWLTMDNPY VVAWHGYGTG RLPPGVRGGP
     RLGYLAAHHL LQEITKMKIG QISEGEGDSL HMTMKEETGF WRTADLLHMR ENVSAEGEVS
     HGASGVCRVP CAVQLPSLWL PCHRVLAQWM AFQSKAHAKV WHLYNDHFRP SQRGKVSIAL
     SSHWIKPQRM TEKNIKECQK SLDFVLGWFA KPIFIDGDYP ESMRSNLSSL LPEFSEAEKK
     YIKGTADFFA LSFGATLSFQ LLDSHMKFQQ LESISLRQLL YWINSEYNKP QIFIVENSWF
     VSGTTKKDDA KYIYYLKKFI METLKAIRYD GVNVFGYTVW SLLDGFEWHR GYSIRRGLFY
     VDFQSHDKKL MPKSSVLFYQ KLIEKNGFPP LPENQPIEGI FPCGFAWGIV DNYIQVDTTP
     AQFLDSSVYV WDVHQTKKLI KVDGVYASQR KRHCVDFAAI RLQISLLQEM HVTHFHFSLK
     WSLILPLGNL SLINHTLVHY YQCFASELLR VNITPVVALW QPMIENQELP VSLAKYGAWE
     NTETVQAFVE YARFCFTSLG DSVKFWITMN EPSVKNLTYT AGHNLLKAHA KVWHLYDKEF
     RRSQKGKISI ALQADWVEPA CPFSRNDQEV ANRILEFDIG WLAEPIFGNG DYPEVMRAWL
     HRINSVDLYN FHLPYFSEDE KKLIQGSFDF FALSHYTTTL VGSEKEDAVK YDHYLEVQMI
     NDITWLHSPS RAAVVPWGLR KLLKWVKSKY GNVPIYVMAN GIDDDQNVVH DKLRVYYIQN
     YINEALKAYT LDDVNLQGYF VYSFNDKTAP KYGLYSYVAN QFEPKPSLKH YREIIDNNGF
     PGPETPELLC PEEVALCPEC HFFRTRKSLL AFISFIFVAF IVTIFFITYY SKRVERRYK
//