ID A0A3M0KMM3_HIRRU Unreviewed; 764 AA.
AC A0A3M0KMM3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Probable RNA-binding protein 46 {ECO:0000256|ARBA:ARBA00021018};
DE AltName: Full=RNA-binding motif protein 46 {ECO:0000256|ARBA:ARBA00030581};
GN ORFNames=DUI87_08954 {ECO:0000313|EMBL:RMC13871.1};
OS Hirundo rustica rustica.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC Hirundo.
OX NCBI_TaxID=333673 {ECO:0000313|EMBL:RMC13871.1, ECO:0000313|Proteomes:UP000269221};
RN [1] {ECO:0000313|EMBL:RMC13871.1, ECO:0000313|Proteomes:UP000269221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chelidonia {ECO:0000313|EMBL:RMC13871.1};
RC TISSUE=Blood {ECO:0000313|EMBL:RMC13871.1};
RA Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT "A high quality draft genome assembly of the barn swallow (H. rustica
RT rustica).";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMC13871.1}.
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DR EMBL; QRBI01000105; RMC13871.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M0KMM3; -.
DR STRING; 333673.A0A3M0KMM3; -.
DR Proteomes; UP000269221; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd19901; DSRM_RBM46; 1.
DR CDD; cd12484; RRM1_RBM46; 1.
DR CDD; cd12492; RRM2_RBM46; 1.
DR CDD; cd12496; RRM3_RBM46; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR InterPro; IPR007053; LRAT_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR044462; RBM46_DSR.
DR InterPro; IPR034434; RBM46_RRM1.
DR InterPro; IPR034435; RBM46_RRM2.
DR InterPro; IPR047837; RBM46_RRM3.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01648; hnRNP-R-Q; 1.
DR PANTHER; PTHR21245; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; 1.
DR PANTHER; PTHR21245:SF3; RNA-BINDING PROTEIN 46-RELATED; 1.
DR Pfam; PF14709; DND1_DSRM; 1.
DR Pfam; PF04970; LRAT; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS51934; LRAT; 1.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000269221};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..764
FT /note="Probable RNA-binding protein 46"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017935305"
FT DOMAIN 51..178
FT /note="LRAT"
FT /evidence="ECO:0000259|PROSITE:PS51934"
FT DOMAIN 275..353
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 355..437
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 450..522
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 548..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 743..764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..570
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 764 AA; 85249 MW; 1B2037B187C1832F CRC64;
MKNPVPQAAS LLLEKLMLLV HLRPLPAGSG GETPPPAPGY YDTSCFKRGD LLEVPRTLFI
HFGIYLGENR VAHLMPDILP SITGDRRQIQ QVVTNKRLIL GVIARTASVR VDTVEDFAYG
GSILVNHMDR LFKDQVLGSE EAARRAEKLV GATAYSLLWN NCEHFVTYCR YGAPVSFQTD
KFCETVKMII RDQRSVLASV LLGVASIVCL AVADMHEENK AAANGCGKIR RGAQNGAALL
ALMEKTGYSM VQQNGQRKFG GPPPGWEGPP PPRGCEVFVG KIPRDMYEDE LVPVFERAGK
IYELRLMMEF SGENRGYAFV MYTTKEEAQL AIKILNNYEI RPGKFIGVCV SLDNCRLFIG
AIPKDKKKEE ILNEMKKVTE GVVDVIVYPN ATDKTKNRGF AFVEYESHRA AAMARRRLIP
GTFQPWGHTI QVDWADPEKV VDEETMQRVK VLYVRNLMIS TTEDKIKAEF NKFKPGVVER
VKKLRDYAFV HFFHREDAVA AMSVMNGKCI DGASIEVTLA KPVNKESSWK QHFNGQISPS
SENLLGFPNK EDSTQKSLGK PASLSIRLNG QHSPGPPEVE RSTYPIFPGI KLTPISMYSL
KLSHFSSAVM HLDYFCHKNS WAPPEYCLYS TTSQDGKILL VYKVLISSIA DDSQSYFMPE
KLCTTVEDAK ELAAQFTLLH LVFSPLSTLL RLEVHPVVEE DSHYYNMEEF THEMQATRKE
EASVPLLCGD HTSTSDIVYQ TNAGEQSGSG MDPGFSKGAL SPDT
//
