ID A0A3M0KQX6_HIRRU Unreviewed; 609 AA.
AC A0A3M0KQX6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 03-MAY-2023, entry version 18.
DE RecName: Full=T-box domain-containing protein {ECO:0000259|PROSITE:PS50252};
GN ORFNames=DUI87_10825 {ECO:0000313|EMBL:RMC13290.1};
OS Hirundo rustica rustica.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC Hirundo.
OX NCBI_TaxID=333673 {ECO:0000313|EMBL:RMC13290.1, ECO:0000313|Proteomes:UP000269221};
RN [1] {ECO:0000313|EMBL:RMC13290.1, ECO:0000313|Proteomes:UP000269221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chelidonia {ECO:0000313|EMBL:RMC13290.1};
RC TISSUE=Blood {ECO:0000313|EMBL:RMC13290.1};
RA Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT "A high quality draft genome assembly of the barn swallow (H. rustica
RT rustica).";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMC13290.1}.
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DR EMBL; QRBI01000106; RMC13290.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M0KQX6; -.
DR STRING; 333673.A0A3M0KQX6; -.
DR Proteomes; UP000269221; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR PANTHER; PTHR11267:SF20; T-BOX TRANSCRIPTION FACTOR TBX18; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000269221};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 129..332
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 24..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 97..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 364..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 609 AA; 65305 MW; 0F890D91F055F677 CRC64;
MADKRRSSPG TTMSLKAHAF SVEALIGAEK QQQQQPPPPP RQPKRRKLGG EDEAAEDEGG
SGCCAKSTPA AAAGRTCGEM DLGCAARAPA GGCEESFLAA SPPASPGGSP KGSRPGSPLP
APQAPRVDLQ GAELWKRFHE IGTEMIITKA GRRMFPAMRV KISGLDPHQQ YYIAMDIVPV
DNKRYRYVYH SSKWMVAGNA DSPVPPRVYI HPDSPASGET WMRQVISFDK LKLTNNELDD
QGHGVGFDLA GVEIILHSMH KYQPRVHVIR KDCGDDLSPV KPIPSGEGGE SLLLPRDSFH
YCHSIPKSTG NLGFLITRLK IDRNPFAKGF RDSGRNRMGL EALVESYAFW RPSLRTLTFE
DIPGIPKQGN AGSSTLLQGS GSGVPSTHPH LLPGSPCSSP AFHLSPNASQ LCTLSPADYT
ACARSGLTLN RYSTSLAETY NRLTNQTSET FAPPRTPSYV GVSSSTTVNM SMSGNDGDAF
SCPQTGLSMQ ISGMSPQLQY IMPSPSSNAF ATNQTHQGSY NTFRLHSPCA LYGYNFSTSP
KLAASPEKIV SSQGSFLGSS PSGTMTDRQM LPPVEGVHLL SSGGQQNFFD SRTLGSLTLS
SSQVSAHMV
//
