ID   A0A3M0KTD7_HIRRU        Unreviewed;       383 AA.
AC   A0A3M0KTD7;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=DM domain-containing protein {ECO:0000259|PROSITE:PS50809};
GN   ORFNames=DUI87_06712 {ECO:0000313|EMBL:RMC16385.1};
OS   Hirundo rustica rustica.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC   Hirundo.
OX   NCBI_TaxID=333673 {ECO:0000313|EMBL:RMC16385.1, ECO:0000313|Proteomes:UP000269221};
RN   [1] {ECO:0000313|EMBL:RMC16385.1, ECO:0000313|Proteomes:UP000269221}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Chelidonia {ECO:0000313|EMBL:RMC16385.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:RMC16385.1};
RA   Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA   Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT   "A high quality draft genome assembly of the barn swallow (H. rustica
RT   rustica).";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00070}.
CC   -!- SIMILARITY: Belongs to the DMRT family.
CC       {ECO:0000256|ARBA:ARBA00006834}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMC16385.1}.
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DR   EMBL; QRBI01000103; RMC16385.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M0KTD7; -.
DR   STRING; 333673.A0A3M0KTD7; -.
DR   Proteomes; UP000269221; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 4.10.1040.10; DM DNA-binding domain; 1.
DR   InterPro; IPR001275; DM_DNA-bd.
DR   InterPro; IPR036407; DM_DNA-bd_sf.
DR   InterPro; IPR026607; DMRT.
DR   InterPro; IPR022114; DMRT1-like.
DR   PANTHER; PTHR12322; DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT; 1.
DR   PANTHER; PTHR12322:SF70; DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 1; 1.
DR   Pfam; PF00751; DM; 1.
DR   Pfam; PF12374; Dmrt1; 1.
DR   SMART; SM00301; DM; 1.
DR   SUPFAM; SSF82927; Cysteine-rich DNA binding domain, (DM domain); 1.
DR   PROSITE; PS40000; DM_1; 1.
DR   PROSITE; PS50809; DM_2; 1.
PE   3: Inferred from homology;
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00070};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW   ProRule:PRU00070};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00070}; Reference proteome {ECO:0000313|Proteomes:UP000269221};
KW   Sexual differentiation {ECO:0000256|ARBA:ARBA00022928};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00070}.
FT   DOMAIN          53..100
FT                   /note="DM"
FT                   /evidence="ECO:0000259|PROSITE:PS50809"
FT   DNA_BIND        53..100
FT                   /note="DM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00070"
FT   REGION          1..48
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          134..154
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          340..383
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        134..153
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        340..360
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   383 AA;  40961 MW;  501A13B66ED2C604 CRC64;
     MPSDTPAFSK PPDVAGPGDK ASGLGKAAAP MAAAPADRGA AAAGKKRPRL PKCARCRNHG
     YSSPLKGHKR FCMWRDCQCN KCSLIAERQR VMAAQVALRR QQAQEEELGI SHPVPLPSVP
     ETFVKKNSGG SSCLSLESSS PMHSTSTAMT AASTPPEGRM LIQDIPSIPS RGPLESTSEL
     VVDSAYYSSF YQPSLYPCYN NLYNYSQYQM AVASEPSSSE TGGTIVGSAM KNSLRSLPAT
     YMPSQSGKQW QVKGMERHHA VSSQYRMCSY YPPASYLGQG VGAPMCLPQI LSSEDVPSAS
     ESKAREVNAM TNKEYFRDAC GTFYQDFLVS LGSRIPVFSP PSSQDSGLGC LSSSSESTKG
     DLECEPPAQP GNFAMSPVQE GGE
//